Toxicology

Dr. Patel is a Reader at the University of Westminster. After completing his PhD at King’s College London, he continued his research experience by undertaking his post-doctoral studies in the laboratory of Professor Cunningham in the Department of Biochemistry at the Wake Forest University School of Medicine, (Winston-Salem, NC, USA). This extensive project involved investigating mechanisms of hepatic mitochondrial ribosome dysfunction in alcoholic liver disease (ALD) using biophysical and proteomic techniques. These studies have led to new avenues in determining the pathology of ALD. His teaching areas at both post-graduate and undergraduate levels include clinical biochemistry, investigative pathology and laboratory investigation. Victor R. Preedy BSc, PhD, DSc, FRSB, FRSPH, FRSC, FRCPath graduated with an Honours Degree in Biology and Physiology with Pharmacology. After gaining his University of London PhD, he received his Membership of the Royal College of Pathologists. He was later awarded his second doctorate (DSc), for his contribution to protein metabolism in health and disease. He is Professor of Clinical Biochemistry (Hon) at King’s College Hospital and Emeritus Professor of Nutritional Biochemistry at King’s College London. He has Honorary Professorships at the University of Hull, and the University of Suffolk. Professor Preedy was the Founding Director and then long-term Director of the Genomics Centre at King’s College London from 2006 to 2020. Professor Preedy has been awarded fellowships of the Royal Society of Biology, the Royal College of Pathologists, the Royal Society for the Promotion of Health, the Royal Institute of Public Health, the Royal Society for Public Health, the Royal Society of Chemistry and the Royal Society of Medicine. He carried out research when attached to the National Heart Hospital (part of Imperial College London), The School of Pharmacy (now part of University College London) and the MRC Centre at Northwick Park Hospital. He has collaborated with international research groups in Finland, Japan, Australia, USA, and Germany. To his credit, Professor Preedy has published over 750 articles, which includes peer-reviewed manuscripts based on original research, abstracts and symposium presentations, reviews and edited books.

• PART 1 TOXICOLOGY AND OXIDATIVE STRESSAGRICULTURAL AND INDUSTRIAL CHEMICALS1. Organophosphate pesticides toxicity, liver cells and linking oxidative stress2. Organophosphate insecticide toxicity and linking oxidative stress3. Organochlorine pesticide toxicity and linking oxidative stress4. Paraquat and reactive oxygen species damage5. Atrazine and oxidative stress6. Fungicide and oxidative stress: a focus on Ziram7. Dioxins and oxidative stress8. Polyaromatic hydrocarbons9. Oxidative stress and neonicotinoid insecticidesMETALS10. Lead toxicity and linking oxidative stress11. Cadmium toxicity and linking oxidative stress (author to link in human aspects)12. Mercury toxicity and linking oxidative stress as indicated by malondialdehyde13. Chromium toxicity and linking oxidative stress14. Arsenic toxicity and linking oxidative damage15. Rare earth element toxicity and genes in linking oxidative stress pathwaysDRUGS, FOOD DERIVED, CHEMICALS AND OTHER AGENTS16. Asbestos fibers and oxidative stress17. Anticancer agents and apoptotic cell death: linking antioxidant genes18. Chlorine toxicity, oxidative stress and impact on isoprostanes19. Ionic liquids as toxic agents and effects reactive oxygen species20. 1,2-Dichloropropanetoxicity and reactive oxygen species21. Aflatoxin B1 toxicity and the role of oxidative stress22. Acetaminophen toxicity: the role of free radical mediated injury23. Alcohol toxicity and the role of oxidative stress24. Air pollution and pulmonary oxidative stress25. Radiation and oxidative stress26. Statins and oxidative stress with statinsPART 2 ANTIOXIDANTS AND TOXICOLOGYAGRICULTURAL AND INDUSTRIAL CHEMICALS27. An overview of antioxidants28. Garlic extract and protection in malathion induced damage: facets of oxidative stress29. Laurocerasus officinalis roem. (cherry laurel) fruit and protection against organophosphate insecticides30. Resveratrol and protection in malathion-induced oxidative stressMETALS31. Vitamin C and protection against arsenic32. Fragaria ananassa and protection against cadmium toxicity33. Citicoline as a nutraceutical and protection in metal poisoning34. Acai fruit (Euterpe oleracea) and protection in mercury related oxidative stress35. Antioxidant N-acetyl-l-cysteine in chromium protection36. Nigella sativa seeds in lead related oxidative stress37. Catechin and protection in cadmium toxicity38. Kolaviron (KV) as an antioxidant: modelling arsenite toxicityDRUGS, FOOD DERIVED, CHEMICALS AND OTHER AGENTS39. Moringa oleifera leaf extract and acetaminophen protection40. All-trans-retinoic acid and protection against renal toxicant p-aminophenol41. Rhus tripartita extracts and ethanol-induced toxicity: glutathione-S-transferases and beyondGENERAL ASPECTS 42. Antioxidants in Cynara scolymus and applications to toxicological sciences43. Antioxidants in Crataegus Monogyna L flowers and applications to toxicological sciences44. Nutrient based RiduROS and use in oxidant stress protection in radiation45. Vernonia amygdalina (Del.) as an antioxidant in toxic injury