Jacqueline E. W. Broerse is Professor of Innovation and Communication in the Health and Life Sciences, and Director of the Athena Institute at Vrije Universiteit Amsterdam.John Grin is Professor of Policy Science, with a focus on System Innovation, at the Department of Political Science at the University of Amsterdam.

• Chapter 1. Introduction John Grin and Jacqueline E.W. BroersePart I Historical Studies on Health System ChangesChapter 2. Historical Studies on Health System Changes Eric BerkersChapter 3 .Key Features of Modern Health Systems; Nature and Historical Evolution Roel van Raak and Fjalar J. de HaanPart II Innovative Practices at the Niche LevelChapter 4. Unraveling Persistent Problems through Analyzing Innovative Practices in Healthcare Tjerk Jan Schuitmaker and Erica ter HaarChapter 5. System Innovation: Workplace Health DevelopmentLenneke Vaandrager, Ingrid Bakker, Maria Koelen, Paul Baart and Tamara RaaijmakersChapter 6. Towards a Sustainable Welfare and Health System in Spain. Experiences with the Case Management Program Jordi Garcés and Francisco RódenasChapter 7. The Making of a Transition Program in the Dutch Care SectorSuzanne van den Bosch and Jord Neuteboom Chapter 8. Trying to Transform Structure, Culture and Practice: Comparing Two Innovation Projects of the Transition Program in Long-Term Care Erica ter Haar-van Twillert and Suzanne van den BoschChapter 9. Contextualizing Evidence in Canadian Healthcare The EXTRA Program David Clements and Dirk EssinkChapter 10. Towards a Needs-Oriented Health Research System Involving Patients in Health Research Janneke E. Elberse, Willem I. de Boer and Jacqueline E.W. BroersePart III ReflectionsChapter 11. The future of health systems: beyond the persistence of contemporary challenges Jacqueline Broerse and John Grin

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Jacqueline E. W. Broerse is Professor of Innovation and Communication in the Health and Life Sciences, and Director of the Athena Institute at Vrije Universiteit Amsterdam.John Grin is Professor of Policy Science, with a focus on System Innovation, at the Department of Political Science at the University of Amsterdam.

• Chapter 1. Introduction John Grin and Jacqueline E.W. BroersePart I Historical Studies on Health System ChangesChapter 2. Historical Studies on Health System Changes Eric BerkersChapter 3 .Key Features of Modern Health Systems; Nature and Historical Evolution Roel van Raak and Fjalar J. de HaanPart II Innovative Practices at the Niche LevelChapter 4. Unraveling Persistent Problems through Analyzing Innovative Practices in Healthcare Tjerk Jan Schuitmaker and Erica ter HaarChapter 5. System Innovation: Workplace Health DevelopmentLenneke Vaandrager, Ingrid Bakker, Maria Koelen, Paul Baart and Tamara RaaijmakersChapter 6. Towards a Sustainable Welfare and Health System in Spain. Experiences with the Case Management Program Jordi Garcés and Francisco RódenasChapter 7. The Making of a Transition Program in the Dutch Care SectorSuzanne van den Bosch and Jord Neuteboom Chapter 8. Trying to Transform Structure, Culture and Practice: Comparing Two Innovation Projects of the Transition Program in Long-Term Care Erica ter Haar-van Twillert and Suzanne van den BoschChapter 9. Contextualizing Evidence in Canadian Healthcare The EXTRA Program David Clements and Dirk EssinkChapter 10. Towards a Needs-Oriented Health Research System Involving Patients in Health Research Janneke E. Elberse, Willem I. de Boer and Jacqueline E.W. BroersePart III ReflectionsChapter 11. The future of health systems: beyond the persistence of contemporary challenges Jacqueline Broerse and John Grin

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Jacqueline E. W. Broerse is Professor of Innovation and Communication in the Health and Life Sciences, and Director of the Athena Institute at Vrije Universiteit Amsterdam.John Grin is Professor of Policy Science, with a focus on System Innovation, at the Department of Political Science at the University of Amsterdam.

• Chapter 1. Introduction John Grin and Jacqueline E.W. BroersePart I Historical Studies on Health System ChangesChapter 2. Historical Studies on Health System Changes Eric BerkersChapter 3 .Key Features of Modern Health Systems; Nature and Historical Evolution Roel van Raak and Fjalar J. de HaanPart II Innovative Practices at the Niche LevelChapter 4. Unraveling Persistent Problems through Analyzing Innovative Practices in Healthcare Tjerk Jan Schuitmaker and Erica ter HaarChapter 5. System Innovation: Workplace Health DevelopmentLenneke Vaandrager, Ingrid Bakker, Maria Koelen, Paul Baart and Tamara RaaijmakersChapter 6. Towards a Sustainable Welfare and Health System in Spain. Experiences with the Case Management Program Jordi Garcés and Francisco RódenasChapter 7. The Making of a Transition Program in the Dutch Care SectorSuzanne van den Bosch and Jord Neuteboom Chapter 8. Trying to Transform Structure, Culture and Practice: Comparing Two Innovation Projects of the Transition Program in Long-Term Care Erica ter Haar-van Twillert and Suzanne van den BoschChapter 9. Contextualizing Evidence in Canadian Healthcare The EXTRA Program David Clements and Dirk EssinkChapter 10. Towards a Needs-Oriented Health Research System Involving Patients in Health Research Janneke E. Elberse, Willem I. de Boer and Jacqueline E.W. BroersePart III ReflectionsChapter 11. The future of health systems: beyond the persistence of contemporary challenges Jacqueline Broerse and John Grin

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