Yongbo Deng received the Ph.D. degree in mechanical engineering from University of Chinese Academy of Sciences, in June of 2012. From July of 2012, he began his Assistant Professor position, in State Key Laboratory of Applied Optics (SKLAO), Changchun Institute of Optics, Fine Mechanics and Physics (CIOMP), Chinese Academy of Sciences. In September of 2014, he derived his Associate Professor position in the same laboratory. During this period, he ever worked in IMTEK, University of Freiburg, for his research collaboration on electromagnetic metamaterial. In May of 2016, he derived the Guest Professor Fellowship from Karlsruhe Institute of Technology (KIT) for his outstanding research on topology optimization-based inverse design methodology. His research interests are topology optimization-based inverse design method with applications in the areas of microfluidics and photonics, and the fabrication processes of MEMS devices.Area of work:Simulation and optimization in hydrodynamics and mechanicsPartial differential equation constrained optimization problem and inverse problem, especially topology optimization, shape optimization and optimal control methods, design and manufacture of MEMS devices, especially the microstructure, microfluidics and photonic devicesFinite element method (Galerkin finite element, mixed finite element, multiscale finite element, vector finite element)  Yihui Wu received her PhD degree from Changchun Institute of Optics, Fine Mechanics and Physics (CIOMP), Chinese Academy of Sciences (CAS) in 1996. She has been a professor of CIOMP since 1999 and now she is a distinguished professor of CAS. She is the group leader of Micro/Nano research in CIOMP. Her research interests are high speed flywheel, spectrometer, Lab-on-a-chip and label-free photonic/phononic biosensors and super resolution imaging.  Zhenyu Liu  received the Ph.D. degree in mechanical engineering from Dalian University of Technology, Dalian, China, in 2000, and Habilitation and Privatdozent from Department of Microsystems Engineering, University of Freiburg, Freiburg, Germany in 2009. From 2000 to 2009, he was a research assistant and a group leader in the Department of Microsystems Engineering, University of Freiburg, Freiburg, Germany. Since 2009, he has served for Changchun Institute of Optics, Fine Mechanics and Physics (CIOMP), Chinese Academy of Sciences, Changchun, China. His research interests are the simulation and optimization of devices in MEMS.

• Introduction.- Topology optimization for unsteady flows.- Topology optimization for fluid flows with body forces.- Topology optimization for two-phase flows.- Combination of topology optimization and optimal control method.- Inverse design of microfluidics using topology optimization.