Tissue Engineering

Clemens van Blitterswijk graduated as cell biologist from Leiden University in 1982, defending his PhD thesis in 1985 at the same university. Today his research focuses on tissue engineering and regenerative medicine, forming a unique basis of multidisciplinary research between materials and life sciences. Van Blitterswijk has authored and co-authored more than 380 peer reviewed papers (H index 90, Scopus); is one of the most frequently cited Dutch scientists in TE; the applicant and co-applicant of over 100 patents; has guided 50 PhD candidates through their thesis as supervisor or co-supervisor and currently has 30 PhD candidates under his supervision. Dr. van Blitterswijk received a number of prestigious international awards including the George Winter award of the European society for Biomaterials, the Career Achievement Award of the Tissue Engineering and Regenerative Medicine International Society and is a member of the KNAW (The Royal Netherlands Academy of Arts and Sciences). Jan de Boer is an experienced University Professor and Chief Scientific Officer with a demonstrated history of working in academia and biotech. As a research professional he is skilled in Stem Cells, Biomaterial Engineering and Regenerative Medicine.  Jan is interested in the molecular complexity of cells and how molecular circuits are involved in cell and tissue function. With a background in mouse and Drosophila genetics, he entered the field of biomedical engineering in 2002 and has since focused on understanding and implementing molecular biology in the field of tissue engineering and regenerative medicine. His research is characterized by a holistic approach to both discovery and application, aiming at combining high throughput technologies, computational modeling and experimental cell biology, to streamline the wealth of biological knowledge to real clinical applications.

• 1. An introduction to tissue engineering; the topic and the book Jorge Alfredo Uquillas, Lorenzo Moroni and Jan de Boer2. Stem cellsMark F. Pittenger and Candace L. Kerr3. Tissue formation during embryogenesis Marcel Karperien, Bernard A.J. Roelen, Robert Passier and Susan Gibbs4. Cellular signalingVanessa LaPointe and Kristopher A. Kilian5. Extracellular matrix as a bioscaffold for tissue engineeringBrian M. Sicari, Ricardo Londono, Jenna L. Dziki and Stephen F. Badylak6. Synthetic biomaterialsAna A. Aldana, Jurica Bauer and Matthew B. Baker7. Degradation of biomaterials Clara Grace Hynes, Emily Morra, Pamela Walsh and Fraser Buchanan8. Cellematerial interactionsHannah Donnelly, Steven Vermeulen, Monica Tsimbouri and Matthew J. Dalby9. Biomaterials discovery: experimental and computational approaches Andrew L. Hook, Aurélie Carlier, Morgan R. Alexander and David A. Winkler10. Microfabrication technology in tissue engineering Minghao Nie, Roman Truckenmüller and Shoji Takeuchi11. Scaffold design and fabrication Dietmar W. Hutmacher, Biranche Tandon and Paul D. Dalton12. Controlled release strategies in tissue engineeringJeffrey J. Rice, Mikaël M. Martino, Sharan Bobbala, Evan A. Scott and Jeffrey A. Hubbell13. Bioreactors: enabling technologies for research and manufacturingDominik Egger, Sabrina Nebel, Marius Gensler, Sebastian Kreb, Jan Hansmann and Cornelia Kasper14. Strategies to promote vascularization, survival, and functionality of engineered tissues Miriam Filippi, Thomas Später, Marietta Herrmann, Matthias W. Laschke, Arnaud Scherberich and Sophie Verrier15. Skin tissue engineering and keratinocyte stem cell therapy Rosalind Hannen, John Connelly, Simon Myers and Nkemcho Ojeh16. Cartilage and bone regenerationAnders Lindahl, Mats Brittberg, David Gibbs, Jonathan I. Dawson, Janos Kanczler, Cameron Black, Rahul Tare and Richard OC. Oreffo17. Tissue engineering of the nervous systemPaul D. Dalton, Kelly L. O’Neill, Ana Paula Pêgo, Giles W. Plant, David R. Nisbet, Martin Oudega, Gary A. Brook and Alan R. Harvey18. Principles of cardiovascular tissue engineering Saray Chen and Smadar Cohen19. Tissue engineering of organ systems Adam M. Jorgensen and Anthony Atala20. Product and process design: scalable and sustainable tissue-engineered product manufacturingEvan Claes, Tommy Heck, Maarten Sonnaert, Filip Donvil, Anaïs Schaschkow, Tim Desmet and Jan Schrooten21. Clinical translationJohan Joly, Marina Marechal, Dieter Van Assche, Malcolm Moos, Jr. and Frank P. Luyten