This volume is the study of micro-organisms from extreme environments, providing a synthesis of advances in the biology, biotechnology, and management of thermophilic organisms, with specific examples drawn largely from thermal springs in Yellowstone National Park. The work addresses the issues of intellectual property rights with regard to the search for novel micro-organisms as sources for pharmaceuticals, and the molecular tools used to address microbial diversity, containing how-to sections for all professionals in ecology and conservation.