Professor Rondal has studied the education of people with intellectual disability for over 40 years. He has won multiple awards for his outstanding scientific research at international conferences, and taught at several universities in Europe and North America.He co-founded the European Down Syndrome Association and was president from 1997 to 2000; he is now President of the Scientific Committee. He is currently a member of the Directorial Board of Down Syndrome International. Professor Rasore-Quartino is President of The European Down Syndrome Association.

• Preface. Authors' Affiliations.Introduction (J-A. Rondal, Liège, and A. Rasore Quartino, Genoa).1 Perspectives on Gene-based Therapies (J-M. Delabar, Paris).2 The Biological Bases of Pharmacological Therapies in Down Syndrome (M. Pritchard, Clayton, Victoria and I. Kola, Rahway, NJ).3 Carbon Metabolism, Immunology and Growth Hormone (C. Romano, Troina, Sicily).4 Medical Therapies in the Lifespan (A. Rasore Quartino, Genoa).5 Language Rehabilitation (J-A. Rondal, Liège).6 Cognitive Rehabilitation (G. Mahoney, Cleveland, OH).7 Psychomotor Rehabilitation in Down Syndrome (G. M. Guazzo, Ottaviano).8 Families and Services (S. Soresi and L. Ferrari, Padua).9 School Inclusion: The Italian Model (L. Cottini, Udine, Friuli, and L. Nota, Padua).10 Mainstream or Special Education for Teenagers with Down Syndrome (S. Buckley, G. Bird, B. Sacks, and T. Archer, Portsmouth).11 Professional Inclusion as Global Therapy for the Individual with Down Syndrome (J. Perera, Palma de Mallorca).12 Quality of Life (C. Baccichetti, Padua).Conclusions (J-A. Rondal, Liège, and A. Rasore Quartino, Genoa).Index.