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Bryan L. Roth - The Serotonin Receptors, Häftad

Häftad, Engelska, 2010

Del i serien The Receptors

The Serotonin Receptors

From Molecular Pharmacology to Human Therapeutics

Av Bryan L. Roth

2889 kr

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Beskrivning
A comprehensive, state-of-the-art review of our current understanding of the molecular and structural biology of 5-HT receptors and their potential use for drug discovery. The authors describe the anatomical, cellular, and subcellular distribution of 5-HT receptors and demonstrate a powerful approach to elucidating their physiological role using knockout mice in which the 5-HT receptors were deleted. They also review our understanding of the physiological role(s) of 5-HT receptors based mainly on studies performed in genetically engineered mice. Highlights include discussions of the behavioral phenotypes of 5-HT receptor knockout animals, the molecular biology and pharmacology of 5-HT receptors, and insights into the complexity of 5-HT receptor signal transduction.
Produktinformation
  • Utgivningsdatum: 2010-11-09
  • Mått: 152 x 229 x 36 mm
  • Vikt: 921 g
  • Format: Häftad
  • Språk: Engelska
  • Serie: The Receptors
  • Antal sidor: 618
  • Förlag: Humana Press Inc.
  • ISBN: 9781617376474
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From the reviews: "This is a compilation of reviews regarding various aspects of serotonin receptor structure and function. ... As a set of reviews, the book can be read by a broad scientific audience. Material of interest to senior scientists and research fellows is present. ... Investigators wishing an up-to-date review of this field will find this book valuable. Those with selected interest, whether evolutionary or structural, will also find useful material. ... is a good, comprehensive set of reviews. ... overall, it is a valuable book." (Eugene A Davidson, Doody's Review Service, February, 2007)

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