The Sepsis Codex

Dr. Jorge Hidalgo is a Professor of Critical Care and the Head of the Division of Critical Care at Karl Heusner Memorial Hospital in Belize, Central America. He is the President Elect of the World Federation of Societies of Critical Care and Intensive Care Medicine. He has won several awards with the highest recognition and the Director of the very prestigious ACP Review Course hosted by the Paraguay Society of Internal Medicine. Due to his outstanding contribution to the Society of Critical Care Medicine he received the Presidential Citation Award. And Global Safar Award, becoming the First Latin American Intensivist to get this Nomination. He is involved in numerous congresses and a well-recognized international speaker. Dr. Javier Perez-Fernandez serves as Medical Director of the Critical Care Services at Baptist Hospital of Miami. He is a Clinical Associate Professor of Medicine at Florida International University, Herbert Wertheim College of Medicine and Professor Pulmonary and Critical Care Medicine at Larkin University, Miami-Dade Florida. He is the Secretary-General of the World Federation of Intensive Care.Dr. Perez-Fernandez manages a large group of critical care physicians, South Florida Critical Care Services, overseeing the operations of seven ICUs with over 350 beds. He has been a regional and national recognized leader during the COVID-19 pandemic with multiple TV and media appearances and consulting services for several national and international organizations. He has been directly involved in the development of Rapid Response Teams, technology implementation and "open ICU” models. He has lectured worldwide and author of many original publications with the Society of Critical Care Medicine.

• PART I: INTRODUCTION1 Sepsis: Past, Present, and Futured Lessons From COVID-19José-Artur Paiva and Jordi Rello2 Sepsis Definitions: A Historical PerspectiveJavier Perez-Fernandez, Arlene C. Torres, and Paola Perez3 The Epidemiology of SepsisJamila HedjalPART II: BASIC CONCEPTS4 Sepsis PathophysiologyMaria Jimena Aleman, Luisa Cruz, Jorge Hidalgo, and Allyson Hidalgo5 Sepsis and MicrocirculationCarlos Enrique A. Orellana Jimenez6 Genetics and SepsisGabriela AlvaradoPART III: DIAGNOSIS AND MONITORING7 Early Detection and ScreeningMárcio Borges Sá and Rafael Zaragoza Crespo8 Diagnosis and Monitoring of SepsisPietro Arina and Mervyn Singer9 Sepsis: Molecular Diagnostics and BiomarkersJohn Lyons and Craig Coopersmith10 Hemodynamic Monitoring: Current Practice and New PerspectivesChristopher Lai and Jean-Louis Teboul11 Point of Care Ultrasound in the Management of SepsisSaad Mahdy, Ahmed F. Hegazy and Tharawt Aisa12 New Approaches and Understanding of SepsisVanessa Fonseca-Ferrer, Sulimar Morales-Colón, Luis Gerena-Montano, WilliamRodríguez-Cintrón, and Gloria M. Rodríguez-Vega13 Sepsis Quality Indicators in the Emergency DepartmentLuis Antonio Gorordo-Delsol and Graciela Merinos-SánchezPART IV: TREATMENT14 Sepsis Treatment: FluidsMichaël Mekeirele, Domien Vanhonacker and Manu L.N.G. Malbrain15 Vasopressor Therapy in Septic ShockRajesh Chandra Mishra, Sharmili Sinha, Reena Shah, Ahsan Ahmed and Ahsina Jahan Lopa16 Mechanical Ventilation in SepsisCarlos Sánchez, Orlando Pérez-Nieto and Eder Zamarrón17 Extracorporeal Membrane Oxygenation for the Support of Patients With Refractory Septic ShockJose Alfonso Rubio Mateo-Sidron18 Antimicrobials in the Management of SepsisJudith Jacobi19 Kidney Support in SepsisJavier Maynar, Helena Barrasa, Alex Martin and Fernando Fonseca20 Hematological Support in SepsisZulmi Aranda, Gerhaldine Morazan and Allyson Hidalgo21 Specific Treatment of Focus Control in SepsisXavier Guirao, Montserrat Juvany, Clara Centeno and Josep Maria Badia22 Sepsis Adjunctive TherapiesJavier Perez-Fernandez and Paola Perez23 Glycemic Control and Stress Ulcer ProphylaxisJanice L. Zimmerman24 Nutrition in SepsisVictor Sanchez NavaPART V: SPECIAL SETTINGS25 Fever in Intensive Care UnitsKazuaki Atagi26 Sepsis--In the Era of Antimicrobial ResistanceRajesh Chandra Mishra, Sharmili Sinha, Reena Shah, Ahsan Ahmed and Ahsina Jahan Lopa27 Factors Underlying Racial and Gender Disparities in Sepsis ManagementRyoung-Eun Ko and Gee Young Suh28 Sepsis in Special PopulationsMarie Baldisseri, Laura S. Johnson, Michael Mazzei and Mary Jane Reed29 Comprehensive Management of Sepsis in PediatricsElisabeth Esteban, Juan Carlos de Carlos, Juan Ignacio Sánchez and Javier Gil Anton30 Maternal SepsisLuis Antonio Gorordo-Delsol, Graciela Merinos- Sánchez, Lucina Nieves-Torres and Jeanette Zúñiga EscorzaPART VI: SPECIAL CONSIDERATIONS31 Role of Preventive Measures in SepsisJorge Sinclair, Jorge E. Sinclair De Frías and Lorenzo Olivero32 Value of the Protocolization and Sepsis Performance Improvement Program in Early IdentificationCarlos Sanchez33 Long-Term Sequelae of SepsisAhmed TahaPART VII: FUTURE OUTLOOK34 New Diagnostic and Therapeutic PerspectivesJuan Carlos Ruiz-Rodríguez, Luis Chiscano-Camón, Erika-Paola Plata Menchaca and Ricard Ferrer35 Artificial Intelligence in SepsisMichiel Schinkel, Ketan Paranjape, Prabath W.B. Nanayakkara and W. Joost Wiersinga