The Science of Hormesis in Health and Longevity

Dr. Rattan is head of the Laboratory of Cellular Ageing, Department of Molecular Biology and Genetics, Aarhus University, Denmark. He is an internationally renowned biogerontologist with more than 30 years of experience in research, teaching, scientific writing and public communication. He is one of the pioneers for the testing and application of hormesis in ageing research and interventions. His research expertise include elucidating the molecular mechanisms of human cellular ageing, with respect to protein synthesis, modifications and turnover. He is the discoverer of the ageing-modulatory effects of kinetin and zeatin, which are now used in several skin care products. He has published more than 250 original research papers and reviews in international journals and books. He has extensive experience and success in compiling and editing/co-editing 15 books for various publishers. He is the founder and current Editor-in-Chief of the journal Biogerontology. He is also the author of popular science books for children in several languages, including English, Punjabi and Danish Dr. Kyriazi is a medical doctor (MD) from the University of Rome, Italy, and after preclinical work in the USA, worked as a clinician in acute medicine in Cyprus, and the UK. He subsequently qualified as a Gerontologist with interest in the biology of ageing and became a Chartered Member of the academic organisation ‘Royal Society of Biology’ in the UK. He also has a post-graduate qualification in Geriatric Medicine from the Royal College of Physicians of London. Other appointments include Member of the Board of Trustees at the Mediterranean Graduate School of Applied Social Cognition, affiliate researcher at the Evolution, Complexity and Cognition Group, University of Brussels, and a Ronin Research Scholar. He co-organises the Cyprus Symposium on ‘Pathways to Indefinite Lifespans’. He is a member of several editorial boards. He is also a Member of the International Committee, Journal of the Spanish Society of Anti-ageing Medicine (SEMAL), Board Member (Directors) of the European Society of Anti-Ageing Medicine (ESAAM), a Peer-review Board Member, Anti-Ageing Conference London, among others. He portfolio comprises over 1000 articles, papers and lectures in the field of healthy ageing. Currently, he works with the ELPIs Foundation for Indefinite Lifespans to study the elimination of age-related degeneration. The research is focused on transdisciplinary models and explores common principles between biology, complexity sciences, evolution, cybernetics, neurosciences, and techno-cultural elements.

• Section 1: HISTORY, TERMINOLOGY AND CHALLENGES1. The dose-response revolution: how hormesis became significantEdward J. Calabrese2. Mild stress-induced hormesis: hopes and challengesEric Le Bourg3. Primary stress response pathways for preconditioning and physiological hormesisSuresh Rattan and Sumangala BhattacharyaSection 2: CLINICAL AND LIFESTYLE HORMESIS4. Remote ischemic preconditioning as a form of hormesisRobert A. Kloner5. Exercise hormesis for health and longevityZsolt Radak6. Nutritional hormesis in a modern environmentHelen R. Griffiths7. Phyto-Hormetins in a Clinical SettingIris R. Bell8. Intermittent fasting-dietary restriction as a biological hormetin for health benefitsGurcharan Kaur Sr.9. Hormetic Responses to Ethanol Ingestion: Focus on Moderation and Cardiovascular Protection Ronald J. Korthuis10. Thermal waters and the hormetic effects of hydrogen sulfide on inflammatory arthritis and wound healing Giovanni ScapagniniSection 3: HOREMTIC STRESSORS11. Hormesis through low dose radiationAlexander Vaiserman12. Metabolic stress – signaling and metabolic adaptationThorsten Heinzel13. DNA damage-induced hormetic responsesChristian Kosan and Zhao-Qi Wang14. Pathogen-induced hormetic responsesReinhard Wetzker and Michael Bauer15. Neuronal stress and its hormetic aspectsBritta Qualmann16. Energetic Stress and Proteodynamics in Aging and LongevityKaryn L. Hamilton17. Repeated electromagnetic field stimulation in aging and healthFelipe Pablo PerezSection 4: HORMETIC INTERVENTIONS AND NOVEL PERSPECTIVES18. Hormesis for healthy ageingSuresh Rattan19. Enhancing sports performance through hormesisDick Thijsse20. Circadian regulation of hormesis for health and longevityAnita Jagota21. A Roadmap for Cross Operationalisation of ResilienceShima Beigi22. Mindfulness, health and longevityJesper Dahlgaard, Mimi Yung Mehlsen, Malene Munk Jørgensen, Rikke Katrine Jentoft Olsen, Niels Gregersen, Anne Maj van der Velden and Antonia Sumbundu23. Buteyko breathing and ketogenic diet as potential hormetins in non-pharmacological metabolic approaches to health and longevityMisha Sakharoff24. Treating neurodegenerative diseases with low doses of ionizing radiationJerry Milton Cuttler25. Interactions with technology as a cognitive, ‘healthy ageing’ hormetic stimulusMarios Kyriazis