Del 9 - Breaking Tolerance to Anti-Cancer Cell-Mediated Immunotherapy

The Resistance of Cervical Cancer to Chemotherapy and its Reversal

Nyhet

Inbunden, Engelska, 2026

AvS. Muthusami,India) Muthusami, S. (Associate Professor and Head, Cancer Research Centre, Karpagam Academy of Higher Education, Coimbatore

2 499 kr

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The Resistance of Cervical Cancer to Chemotherapy and its Reversal provides a holistic understanding of cervical cancer development, immune-evading mechanisms of HPV, immunotherapies available, methods to study cervical cancer and the development of newer drugs. Content shows the involvement of signaling pathways during chemoresistance in cervical cancer, the involvement of genes in drug resistance, and introduces long noncoding RNAs as novel biomarkers.

In 10 chapters, this book first provides an introduction and history of cervical cancer; next, it discusses the influence of viruses on cervical cancer and finally, it describes therapies to overcome chemotherapy resistance in cervical cancer. This is the perfect reference to provide the fundamental base of knowledge needed for oncologists, pharmacologists, translational investigators, immunotherapists, scientists, and clinicians interested in building a comprehensive understanding of the field.

Focuses on the aspects of cervical cancer resistance towards therapies such as chemoresistance and radioresistance
Discusses the sensitizing agents that are being developed for the improvement of current therapies and better management of cervical cancer
Identifies the molecular mechanism of HPV integration and cervical cancer development

Produktinformation

Utgivningsdatum2026-03-27
Mått191 x 235 x undefined mm
Vikt450 g
FormatInbunden
SpråkEngelska
SerieBreaking Tolerance to Anti-Cancer Cell-Mediated Immunotherapy
Antal sidor364
FörlagElsevier Science
ISBN9780443223525

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Dr. Sridhar Muthusami completed his Ph.D in endocrinology in the year 2011 from the University of Madras, India. His doctoral study was aimed at delineating the molecular mechanism underlying the anabolic actions of Cissus quadrangularis, an indigenous herb believed to exert anabolic effects on bone cells through IGFR. After completing his Ph.D, he has joined for his Postdoctoral work in the department of Radiation Oncology, Chungbuk National University, South Korea. He has worked on the role of Epidermal growth factor/receptor (EGF/EGFR) signaling and its regulation of oncoprotein Fused Toes Homolog (FTS) in cervical cancer cells from 2011 to 2014. He is also involved in the identifying the role of T0070907/EGCG/cordycepin on cervical cancer cells. Since 2015, he moved to the department of biochemistry, Karpagam Academy of Higher Education (Deemed to be University) and serving as Associate Professor and Head at Cancer Research Centre working in the area of development of EGFR TKIs for the treatment/management of cervical cancer/pancreatic cancer.

1. Wnt signalling and cervical cancer2. Pharmacologial targets of cervical cancer3. PD-1, HPV and cervical cancer4. Radiotherapy and cervical cancer5. HPV and cervical cancer6. EGFR and cervical cancer7. Protein engineering for cervical cancer8. Anti-virals and cervical cancer9. Advances in cytological screening for cervical cancer10. microRNA and cervical cancer11. Computer aided drug designing for cervical cancer12. Nanoparticles for the treatment of cervical cancer

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