'What is life? What universal principles apply to any biosphere? Our efforts to answer these deep questions are stymied because of our biased, Earth-bound perspective with only one kind of (known) life. In a book rich with original ideas and lucid insights, science philosopher Carol E. Cleland considers life from the perspective of what we don't know - the limitations, hidden biases, sloppy definitions, and false assumptions that may lead us astray. From 'shadow biospheres' on Earth, to artificial life in the lab, to alien lifeforms in distant galaxies, Cleland expands our minds and leads us to rethink what we thought we knew.' Robert Hazen, Carnegie Institution for Science, Washington