Reinhard Schweitzer-Stenner is a vibrational spectroscopist and biophysical chemist whose research focuses on the structure, dynamics, and function of biological molecules. Over a career spanning more than 40 years, he has combined spectroscopic, theoretical, and computational approaches to investigate heme proteins, peptides, and other complex biomolecular systems, contributing to advances in molecular spectroscopy, biophysics, and physical chemistry. He is Emeritus Professor of Chemistry at Drexel University, where he served on the faculty for nearly two decades, becoming Full Professor in 2009 before retiring in 2022 and remaining research active. His international academic career has included appointments in Germany, Puerto Rico, and the United States, including at Universität Bremen, where he received his habilitation in 1990, the University of Michigan, Ann Arbor, and the University of Puerto Rico, Río Piedras, before joining Drexel in 2003. His teaching has covered biophysics, spectroscopy, physical chemistry, atomic and molecular physics, statistical thermodynamics, and bioinorganic chemistry at undergraduate and graduate level, reflecting a rare breadth across the physical and biological chemistry interface.

• 1. Introduction2. Intramolecular and Intermolecular Interactions3. Protein Dynamics4. Protein Folding and Unfolding5. Intrinsically disordered proteins and poly-peptides6. Misfolding and peptide/protein aggregation7. Summary and Outlook

Reinhard Schweitzer-Stenner is a vibrational spectroscopist and biophysical chemist whose research focuses on the structure, dynamics, and function of biological molecules. Over a career spanning more than 40 years, he has combined spectroscopic, theoretical, and computational approaches to investigate heme proteins, peptides, and other complex biomolecular systems, contributing to advances in molecular spectroscopy, biophysics, and physical chemistry. He is Emeritus Professor of Chemistry at Drexel University, where he served on the faculty for nearly two decades, becoming Full Professor in 2009 before retiring in 2022 and remaining research active. His international academic career has included appointments in Germany, Puerto Rico, and the United States, including at Universität Bremen, where he received his habilitation in 1990, the University of Michigan, Ann Arbor, and the University of Puerto Rico, Río Piedras, before joining Drexel in 2003. His teaching has covered biophysics, spectroscopy, physical chemistry, atomic and molecular physics, statistical thermodynamics, and bioinorganic chemistry at undergraduate and graduate level, reflecting a rare breadth across the physical and biological chemistry interface.

• 1. Introduction2. Intramolecular and Intermolecular Interactions3. Protein Dynamics4. Protein Folding and Unfolding5. Intrinsically disordered proteins and poly-peptides6. Misfolding and peptide/protein aggregation7. Summary and Outlook

Reinhard Schweitzer-Stenner is a vibrational spectroscopist and biophysical chemist whose research focuses on the structure, dynamics, and function of biological molecules. Over a career spanning more than 40 years, he has combined spectroscopic, theoretical, and computational approaches to investigate heme proteins, peptides, and other complex biomolecular systems, contributing to advances in molecular spectroscopy, biophysics, and physical chemistry. He is Emeritus Professor of Chemistry at Drexel University, where he served on the faculty for nearly two decades, becoming Full Professor in 2009 before retiring in 2022 and remaining research active. His international academic career has included appointments in Germany, Puerto Rico, and the United States, including at Universität Bremen, where he received his habilitation in 1990, the University of Michigan, Ann Arbor, and the University of Puerto Rico, Río Piedras, before joining Drexel in 2003. His teaching has covered biophysics, spectroscopy, physical chemistry, atomic and molecular physics, statistical thermodynamics, and bioinorganic chemistry at undergraduate and graduate level, reflecting a rare breadth across the physical and biological chemistry interface.

• 1. Introduction2. Intramolecular and Intermolecular Interactions3. Protein Dynamics4. Protein Folding and Unfolding5. Intrinsically disordered proteins and poly-peptides6. Misfolding and peptide/protein aggregation7. Summary and Outlook