The Microbiome in Health and Disease

Dr. Jun Sun is a tenured Professor of Medicine at the University of Illinois at Chicago (UIC), U.S.A.. She is an elected fellow of American Gastroenterological Associate (AGA) and American Physiology Society (APS). She is the Chair-elected for the AGA microbiome section. Her research interests are host-microbiome interactions in inflammation and cancer. Her key achievements include 1) characterization of vitamin D receptor regulation of gut microbiome in intestinal homeostasis and inflammation, 2) identification of dysbiosis and intestinal dysfunction in Amyotrophic lateral sclerosis (ALS), 3) characterization of bacteria in regulating intestinal stem cells and leading to cancer, and 4) identification and characterization of the Salmonella protein AvrA in host-bacterial interactions. Dr. Sun has published over 170 scientific articles in peer-reviewed journals, including Gut, Gastroenterolog, Cell Stem Cells, Nature Genetics, JBC, Autophagy, American Journal of Pathology, & American Journal of Physiology-GI. She is the leading editor of three books, including a recent Nature/Spring book entitled “Mechanisms underlying host-microbiome interactions in pathophysiology of human diseases.” This book has shown a novel theme and multiple disciplinary topics of microbiome research for broad audience. She is the author of Nature/Spring book “Statistical Analysis of Microbiome Data with R. This timely book addresses the statistical modelling and analysis of microbiome data using cutting-edge R software. She serves the editorial board of more than 10 peer-reviewed international scientific journals. She services study sections for the NIH, American Cancer Society, and other national and international research foundations. She has been invited to chair meetings on microbiome, be a keynote speaker, and to write reviews, editorials, and comments on microbiome in human diseases for peer-reviewed journals. She is actively involved in advocating microbiome research at the international, national and institutional levels. Her research is supported by the NIH, DOD, and other research awards.Dr. Sun is a believer of scientific art and artistic science. She enjoys writing her science papers in English and poems in Chinese. She teaches her medical fellows biomedical knowledge and also the way to translate the Chinese poems. In addition to her research papers and books, her poetry collection《让时间停留在这一刻 》“Let time stay still at this moment” is published in 2018 by the Chinese Literature and History Press.

• 1. Introduction: Microbiome in health and diseaseJun Sun2. The Infant Microbiome and Implications for CNS DevelopmentElaine O. Petrof3. Microbiome (Virome) and virus infection Lijuan Yuan4. Gut Microbiota in Reductive Drug MetabolismYoung Jeong and Hunwoo Lee5. Relationship between T cells and microbiota in health and diseasesTeruyuki Sano6. Oral and intestinal bacterial exotoxins: potential linked to carcinogenesisIkuko Kato and Jun Sun7. Mucosa microbiome of gastric lesions: fungi and bacteria interactionsYunsheng Yang8. Nutrition and microbiotaWendy Dahl9. Microbiota derived factors as drivers of type 1 diabetesEmma Hamilton-Williams10. Interactions of Probiotics and Prebiotics with the Gut MicrobiotaSusana Marta Isay Saad11. Bioinformatics in microbiomeyinglin xia12. Microbiome and cancer treatment: are we ready to apply in clinics?Stephen L. Chan