Del 56 - Annual Reports in Medicinal Chemistry

The Design of Covalent-Based Inhibitors

Inbunden, Engelska, 2021

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Annual Report on Medicinal Chemistry series, highlights new advances in the field with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

Provides the authority and expertise of leading contributors from an international board of authors
Presents the latest release in the Annual Report on Medicinal Chemistry series
Updated release includes the latest information on The Design of Covalent-Based Inhibitors

Produktinformation

Utgivningsdatum2021-07-09
Mått152 x 229 x 20 mm
Vikt610 g
FormatInbunden
SpråkEngelska
SerieAnnual Reports in Medicinal Chemistry
Antal sidor298
FörlagElsevier Science
ISBN9780128216897

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Kemi inom Naturvetenskap och teknik
Farmakologi inom Medicin

PrefaceRichard Andrew Ward and Neil Grimster1. The history of covalent inhibitorsRenato A. Bauer2. Kinetic Mechanisms of Covalent InhibitionClaire Louise McWhirter3. Covalent Drugs in Development for Immune-Mediated DiseasesLeonard Sung4. Chemistry Perspectives of Reversible Covalent DrugsJianmin Gao5. Design of Next-Generation Covalent Inhibitors: Targeting Residues Beyond CysteineLyn Jones6. Boron and Covalent InhibitionAndrew Leach7. Measuring and predicting warhead and residue reactivityChristopher Rowley8. Computational Support of Structure-based Targeted Covalent Inhibitor DesignRobert Abel9. Novel approaches to covalent inhibitionNir London10. The future of covalent inhibitionGyorgy M. Keseru