The Cardiovascular System

Hussein Sabit graduated from Ain Shams University, Cairo and received his BSc in Genetics, where he also get his MSc in Microbial Genetics and PhD in Molecular Genetics. He joined Misr University for Science and Technology, Egypt as TA, Assistant Professor. Has been promoted to Associate Professor of Molecular Genetics, and Full Professor in Cancer Epigenetics. His research interest is Cancer Genetic/Epigenetic basis of carcinogenesis, genome editing via CRISPR/Cas9, studying the anti-apoptotic genes and its relations with BC progression, investigating the DNA methylation levels controlling carcinogenesis of BC, studying the chromatin remodelling as a main mechanisms leading to cancer using ChIP assays and others. He published 28 articles; most of them is the main field of Cancer Genetics/Epigenetics. He is the director of Cancer Epigenetics Research Unit (CERU) at MUST, where he leads a research team of postgrad students.

• 1. Organoid Culture System as Innovative Model of Heart Stem Cell-Based Cardiac Development and Diseases2. Innovated Therapeutic Gene Editing Technologies in Stem Cell Engineering and Cardiovascular Disorders and Diseases3. Cardiotoxivity and Cancer Therapy: Mechanisms, Implications, and Mitigation Strategies4. Advances in stem cell-based therapy of cardiovascular diseases and disorders5. Derivation and Application of Embryonic Stem Cells as a Model for Heart Development Diseases and Disorders6. The Potential of Mesenchymal Stem Cell Related Therapies for Cardiovascular Diseases and Disorders7. Stem Cell Innovation in Cardiovascular Disease, Repair and Regeneration: General Conclusion, Challenges and Prospective