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Vasculitis is a condition that involves inflammation of the blood vessels. The condition occurs if the immune system attacks the blood vessels by mistake. This may happen as the result of an infection, a medicine, or another disease or condition.This new edition is a complete guide to the diagnosis and management of vasculitis.Divided into six sections, the book begins with an overview of the epidemiology, genetics and classification of vasculitis, followed by discussion on basic science and pathological aspects.The next sections cover imaging modalities used to assess and diagnose disease activity, and clinical manifestations according to organ system or individual vasculitis syndromes.Section five discusses disease management techniques, and the book concludes with in depth examination of more than 20 individual vasculitis syndromes.The second edition has been extensively revised and features new topics including DADA2 and VEXAS syndrome, bringing clinicians fully up to date with the latest advances in their field.The comprehensive text is further enhanced by clinical images and figures.The previous edition (9789351526520) published in 2015.
Aman Sharma MD FAMS FIACM FICP FACR FRCPProfessor, Clinical Immunology and Rheumatology Wing, Department of Internal Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India
SECTION 1: INTRODUCTIONChapter 1. Epidemiology of VasculitisChapter 2. Genetics of VasculitisChapter 3. Classification of VasculitisSECTION 2: BASIC SCIENCESChapter 4. Neutrophils in ANCA-associated VasculitisChapter 5. Antineutrophil Cytoplasmic AntibodiesChapter 6. Animal Models of ANCA VasculitisChapter 7. Pathogenesis of VasculitisChapter 8. Pathology of Cutaneous VasculitisChapter 9. Pathology of Pulmonary VasculitisChapter 10. Pathology of Renal VasculitisChapter 11. Pathology of Vasculitis of the Central Nervous System and Peripheral NervesChapter 12. Pathology of Gastrointestinal VasculitisSECTION 3: IMAGING MODALITIESChapter 13. Imaging in VasculitisChapter 14. Positron Emission Tomography in the Systemic VasculitidesSECTION 4: CLINICAL MANIFESTATIONS ACCORDING TO ORGAN INVOLVEMENTChapter 15. Cutaneous VasculitisChapter 16. Retinal VasculitisChapter 17. Cardiac ManifestationsChapter 18. Pulmonary ManifestationsChapter 19. Renal ManifestationsChapter 20. Neurological ManifestationsChapter 21. Vasculitic NeuropathyChapter 22. Gastrointestinal ManifestationsChapter 23. Head and Neck ManifestationsSECTION 5: PRINCIPLES OF MANAGEMENTChapter 24. Approach to Childhood VasculitisChapter 25. Approach to an Adult with Systemic VasculitisChapter 26. Assessment of Disease Activity and DamageChapter 27. Newer and Future Treatments of Systemic VasculitidesSECTION 6: INDIVIDUAL VASCULITIS SYNDROMESChapter 28. Giant Cell Arteritis and Polymyalgia RheumaticaChapter 29. Takayasu’s ArteritisChapter 30. Kawasaki DiseaseChapter 31. Polyarteritis NodosaChapter 32. Deficiency of Adenosine Deaminase 2Chapter 33. Autoinflammatory Vasculitic SyndromesChapter 34. VEXAS SyndromeChapter 35. Granulomatosis with PolyangiitisChapter 36. Microscopic PolyangiitisChapter 37. Eosinophilic Granulomatosis with PolyangiitisChapter 38. Immunoglobulin A VasculitisChapter 39. Primary Angiitis of the Central Nervous SystemChapter 40. Behcet’s Disease: Diagnosis and ManagementChapter 41. Cryoglobulinemic VasculitisChapter 42. Relapsing PolychondritisChapter 43. Immunoglobulin G4-related DiseaseChapter 44. Infection-associated VasculitisChapter 45. Vasculitis MimicsChapter 46. Secondary VasculitisChapter 47. Cogan’s SyndromeChapter 48. Cancer-associated VasculitisChapter 49. Pregnancy and VasculitisChapter 50. Prevention and Management of Infections