TCTP/tpt1 - Remodeling Signaling from Stem Cell to Disease

Häftad, Engelska, 2018

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This book highlights the role of the Translationally Controlled Tumor Protein (TCTP) in cell signaling, cell fate and the resulting connection to disease development.

Produktinformation

Utgivningsdatum2018-05-23
Mått155 x 235 x undefined mm
FormatHäftad
SpråkEngelska
SerieResults and Problems in Cell Differentiation
Antal sidor309
FörlagSpringer International Publishing AG
ISBN9783319884530

Tillhör följande kategorier

Onkologi inom Medicin
Biokemi inom Naturvetenskap och teknik
Cellbiologi inom Naturvetenskap och teknik

1 Introduction: How we encountered TCTP and our purpose in studying it.- 2 Structural insights into TCTP and its interactions with ligands and proteins.- 3 Structure-Function relationship of TCTP.- 4 The Translational Controlled Tumour Protein TCTP: Biological Functions and Regulation.- 5 Current understanding of the TCTP interactome.- 6 Role and fate of TCTP in protein degradative pathways.- 7 Roles of the Translationally Controlled Tumor Protein (TCTP) in plant development.- 8 Function of Translationally controlled tumor protein in organ growth: Lessons from Drosophila studies.- 9 Translationally controlled tumor protein (TCTP/HRF) present in animal venoms.- 10 Tctp in Neuronal Circuitry Assembly.- 11 Elusive role of TCTP protein and mRNA in cell cycle and cytoskeleton regulation.- 12 TCTP protein and the cellular response to ionizing radiation-induced DNA damage.- 13 TCTP has a crucial role in the different stages of Prostate Cancer malignant progression.- 14 Role of TCTP for cellular differentiation and cancer therapy.- 15 Targeting TCTP with sertraline and thioridazine in cancer treatment.- 16 . History of Histamine Releasing Factor (HRF)/TCTP including a Potential Therapeutic Target in Asthma and Allergy.