Targets for Cancer Chemotherapy

• Cancer Chemotherapy Based on E2F and the Retinoblastoma Pathway. Myc Oncoproteins as Targets for Therapeutic Intervention in Tumorigenesis. The AP-1 Family of Transcription Factors: Structure, Regulation, and Functional Analysis in Mice. Hypoxia-Induced Factor-1 as a Target for Anticancer Therapy. Nuclear b-Catenin Signaling as a Target for Anticancer Drug Development Histone Acetyltransferases as Potential Targets for Cancer Therapies. Histone Deacetylases. Cyclin-Dependent Kinases and Their Small-Molecule Inhibitors in Cancer Therapy. Mitogen-Activated Protein Kinase Cascades as Therapeutic Targets in Cancer. Mdm2 and ARF. The Breast Cancer Susceptibility Genes, BRCA1 and BRCA2. Human Papillomavirus Targets for Therapeutic Intervention. Apoptin as an Anticancer Therapy. E2F and Cancer Chemotherapy. Hypoxic Signaling Pathways as Targets for Anticancer Therapy. Androgen Receptor and Estrogen Receptors. Index.

'This book will be of interest to drug development professionals and oncology researchers. Specific chapters make good reviews for clinicians interested in emerging therapies and may also be useful for students." - Today's Life Science "The book is included in the successful series of publications "Cancer Drug Discovery and Development" form Humana Press. It will be of interest both to clinicians and to laboratory cancer researchers, as well as to people who are interested in recent achievements in molecular oncology, which gives new hope for better treatment of caner patients." - Neoplasma