Targeting of Drugs

• The Structure of Different Types of Liver Cells in Relation to Uptake and Exchange Processes.- The Lymphatic System in Drug Targeting: An Overview.- The Hepatic Receptor for Asialoglycoproteins: Search for a Function.- The Galactose-Particle Receptor on Liver Macrophages: Biological Function and Implications for Clearance of Particulate Material.- Free Radicals in Health and Disease: Implications for Drug Delivery and Targeting.- Monoclonal Antibodies and Drug Targeting in Cancer.- Immunotoxins in Cancer Therapy.- Techniques for Ex-Vivo Bone Marrow Treatment with Immunotoxins.- The Potential of Membrane-Acting Toxins for Targeted Cancer Therapy.- In Vivo Uptake and Processing of Liposomes by Parenchymal and Non-parenchymal Liver Cells: Application to Immunotherapeutic Treatment of Hepatic Metastases.- Platelet Activating Factor, a Potent Mediator of Allergy, as a Structural Component of Phosphatidylcholine Vesicles.- Phospholipid Stereospecificity in Liposomal Modulation of Nitrogen Mustard Action.- Niosomes: A Putative Drug Carrier System.- The Immunoadjuvant Action of Liposomes: Optimization Studies.- Targeting of Antigens to Antigen-Presenting Cells and Their Activation: A Requirement for Vaccine Development.- Targeting Using Physical Approaches and Particulate Drug Carriers: Interaction with the Biological Milieu.- Pragmatic Approaches to Delivery of Peptides and Proteins as Drugs.- Reconstituted Influenza Virus Envelopes as a Potential Carrier for Fusion-Mediated Microinjection of Macromolecules into Living Cells.- Contributors.

From Book News, Inc. Proceedings of the conference held June 20-July 1, 1987 in Cape Sounion, Greece. Contributors deal in depth with numerous biological milieus as travelled space for carriers enroute to their destination, difficulties arising from unfavorable milieu-carrier interactions, and ways to circumvent such difficulties. Situations where proposed uses would or would not be realistic are also identified. Liberal use of graphics. Produced from uniform typescript. Annotation copyright Book News, Inc. Portland, Or.