Targeted Cancer Treatment in Silico

Countless medical researchers over the past century have been occupied by the search for a cure of cancer. So far, they have developed and implemented awide rangeof treatment techniques, including surgery, chemo- and radiotherapy, antiangiogenic drugs, small molecule inhibitors, and oncolytic viruses.However, patterns of these treatments' effectiveness remain largely unclear, and a better understanding of how cancer therapies work has become akey research goal.Cancer Treatment in Silicoprovides the first in-depth study of approaching this understanding by modeling cancer treatments, both mathematically and through computer simulations. The main goal of this book is to help expose students and researchers to in silico methods ofstudying cancer.It isintended forboth the applied mathematics and experimental oncology communities,asmathematicalmodelsare playing an increasingly important roleto supplement laboratory biology in the fight against cancer. Written at a level that generally requires little technical background,the workwill be a valuable resource for scientists and students alike.