Del i serien Methods in Molecular Biology

T-Cell Repertoire Characterization

Inbunden, Engelska, 2022

2 139 kr

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Chapters broadly cover the emerging new T cell subsets, sequencing technologies for capturing TCR repertoire, and computational tools for analyzing an ever-growing TCR repertoire, with a particular focus on how to link the sequence with TCR antigen specificity.

Produktinformation

Utgivningsdatum2022-09-11
Mått178 x 254 x 28 mm
Vikt954 g
FormatInbunden
SpråkEngelska
SerieMethods in Molecular Biology
Antal sidor391
FörlagSpringer-Verlag New York Inc.
ISBN9781071627112

Tillhör följande kategorier

Onkologi inom Medicin
Cellbiologi inom Naturvetenskap och teknik

Ligand identification for Orphan MHC-agnostic T-cell receptors by whole genome CRISPR-Cas9 screening.- Discovery of HLA-E-presented epitopes: MHC-E/peptide binding and T cell recognition.- Identification of human antigen-specific T cells using class II MHC tetramer staining and enrichment.- Characterization of KIR+CD8+ regulatory T cells in humans by scRNA- and TCR-seq.- Detection of α-synuclein-specific T cells in Parkinson’s disease.- The intra-tumoural T cell receptor repertoire – steps towards a useful clinical biomarker.- Enriching and Characterizing T-Cell Repertoires from 3’ Barcoded Single-Cell Whole Transcriptome Amplification Products.- Tetramer associated T cell receptor sequencing.- T-cell Repertoire Characterization.- Characterization of mouse CD4 TCR and its targeting antigen.- Rapid identification of MHCII-binding peptides through microsphere-assisted peptide screening (MAPS).- A high throughput strategy for T-Cell Receptor cloning and expression.- Epitope-specific T-cell receptor data and tools in the Immune Epitope Database.- A Bioinformatic Framework for Dissecting the Dynamics of T cells from Single-Cell Transcriptome.- Grouping T-Cell Antigen Receptors by Specificity.- Flexible Distance-Based TCR Analysis in Python with tcrdist3.- Multimodal T cell analysis with CoNGA.

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