Systems Biology

Definitions and Perspectives

Inbunden, Engelska, 2005

AvLilia Alberghina,Lilia Alberghina,Hans V. Westerhoff

2 769 kr

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The wealth of genomic and post-genomic data needs to be structured so that the understanding of complex cellular processes can be achieved by creating computational models able to describe and predict phenotypes at the cell or organism level in health and disease. This book provides a detailed presentation of systems biology studies that are paving the way towards the above-mentioned goal and discusses the most efficient experimental and computational strategies for this purpose. The potential benefits for bioindustry, in particular the discovery of new drugs and better management, are also presented.

Produktinformation

Utgivningsdatum2005-09-22
Mått155 x 235 x 31 mm
Vikt890 g
FormatInbunden
SpråkEngelska
SerieTopics in Current Genetics
Antal sidor408
Upplaga2005
FörlagSpringer-Verlag Berlin and Heidelberg GmbH & Co. KG
ISBN9783540229681

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Biovetenskap inom Naturvetenskap och teknik

Systems Biology of Apoptosis.- Mathematical Modeling of the Wnt-Pathway.- Modeling Signaling Pathways – A Yeast Approach.- Mechanistic and Modular Approaches to Modeling and Inference of Cellular Regulatory Networks.- Scientific and Technical Challenges for Systems Biology.- Integration of Metabolic and Signaling Networks.- From Isolation to Integration, a Systems Biology Approach for Building the Silicon Cell.- What’s Systems Biology: From Genes to Function and Back.- Systems Biology: Recent Developments and New Trends.- A Modular Systems Biology Analysis of the Cell Cycle Entrance into S Phase.- Metabolic Control Analysis.- Mesoscopic Kinetics and its Applications in Protein Synthesis.- E. coli Glycolysis.- Kinetic Modeling of the E. coli Metabolism.- No Music without Melody: How to Understand Biochemical Systems by Understanding Their Dynamics.- Systems Biology of the Yeast Cell Cycle Engine.- Quantification of in vivo Molecular Fluxes: A Key Methodology for Metabolic Systems Biology.-Modeling the E. coli cell: The Need for Computing, Cooperation, and Consortia.