• Genomics, Biological Features, and Biotechnological Applications of Escherichia coli B: “Is B for better?!”.- Escherichia coli Genome Engineering and Minimization forthe Construction of a Bioengine.- Multi-Omics Data-Driven Systems Biology of E. coli.- A Medium-Throughput Structural Proteomics Approach Applied to the Genome of E. coli.- Resources for Escherichia coli Systems Biology.- The Multiple Scientific Disciplines Served by EcoCyc.- Analysis of E. coli Network.- Sensory Transduction Network of E. coli.- Genome-Scale Reconstruction, Modeling, and Simulation of E. coli?s Metabolic Network.- Kinetic Modeling of E. coli Enzymes: Integration of in vitro Experimental Data.- Dynamic Modeling of the Central Metabolism of E. coli – Linking Metabolite and Regulatory Networks.- Genome-Scale Models and the Genetic Basis for E. coli Adaptation.- Organisation of Complex Escherichia coli Promoters.- Plasmid Regulation and Systems-Level Effects on Escherichia coli Metabolism.- Systems-Level Analysis of Protein Quality in Inclusion Body-Forming Escherichia coli Cells.- Mechanistic Challenges and Engineering Applications of Protein Export in E. coli.- Engineering E. coli Central Metabolism for Enhanced Primary Metabolite Production.- Glucose and Acetate Metabolism in E. coli – System Level Analysis and Biotechnological Applications in Protein Production Processes.- Performance Characteristics for Sensors and Circuits Used to Program E. coli.- Systems Metabolic Engineering of E. coli.

"This is a very interesting and powerful collection of chapters covering a wide spectrum of systems biology frontiers in E. coli and written by recognized leaders in the field... a must have publication for years to come" Professor Eleftherios Terry Papoutsakis, University of Delaware, U.S.A.