Synthetic Biology

Shailza Singh is working as Scientist D at National Centre for Cell Science, Pune. She works in the field of Computational and Systems Biology wherein she is trying to integrate the action of regulatory circuits, cross-talk between pathways and the non-linear kinetics of biochemical processes through mathematical models. The current thrust in her laboratory is to explore the possibility of network-based drug design and how rationalized therapies may benefit from Systems Biology. She has published a book with Springer, titled 'Systems Biology Application in Synthetic Biology'. She is the recipient of RGYI (DBT), DST-Young Scientist and INSA (Bilateral Exchange Programme). She is the reviewer of various international and national grants funded from government organizations.

• Chapter 1. Integrated Systems and Chemical biology approaches for targeted therapies.- Chapter 2. Application of bioengineering in revamping human health.- Chapter 3. Integrative Omics for Interactomes.- Chapter 4. Studying parasite gene function and interaction through ribozymes and riboswitches design mechanism.- Chapter 5. Genome microbiology for Synthetic applications.- Chapter 6. Medicinal Application of Synthetic Biology.- Chapter 7. Computational tools for applying multi-level models to Synthetic Biology.- Chapter 8. Computational techniques for a comprehensive understanding of different genotype-phenotype factors in biological systems and their applications.- Chapter 9. Alignment-free analyses of nucleic acid sequences using graphical representation.- Chapter 10. Modern Approaches in Synthetic Biology: Genome Editing,Quorum Sensing and Microbiome Engineering.- Chapter 11. Synthetic Probes, their applications & designing.- Chapter 12. Omics Based Nanomedicine.- Chapter 13. Characterization of plant genetic modifications using Next Generation Sequencing.