Surgical Management of Advanced Pelvic Cancer

Michael E. Kelly is an Advanced Pelvic Exeneterative Fellow at the Department of Surgery, St. Vincent’s University Hospital, Dublin, Ireland.  Desmond C. Winter is a Consultant Colorectal Surgeon and Clinical Professor at the Department of Surgery, St. Vincent’s University Hospital, Dublin, Ireland.

• List of Contributors viiiPreface xiii1 From Early Pioneers to the PelvEx Collaborative 1Éanna J. Ryan and P. Ronan O’Connell2 The Role of the Multidisciplinary Team in the Management of Locally Advanced and Recurrent Rectal Cancer 12Dennis P. Schaap, Joost Nederend, Harm J.T. Rutten, and Jacobus W.A. Burger3 Preoperative Assessment of Tumor Anatomy and Surgical Resectability 17Akash M. Mehta, David Burling, and John T. Jenkins4 Neoadjuvant Therapy Options for Advanced Rectal Cancer 32Alexandra Zaborowski, Paul Kelly, and Brian Bird5 Preoperative Optimization Prior to Exenteration 45Marta Climent and Miguel Pera6 Patient Positioning and Surgical Technology 52Ben Creavin, Michael E. Kelly, and Desmond C. Winter7 Intraoperative Assessment of Resectability and Operative Strategy 62Rory Kokelaar, Dean Harris, and Martyn Evans8 Anterior Pelvic Exenteration 73Jan W.A. Hagemans, Jan M. van Rees, Joost Rothbarth, Cornelis Verhoef , and Jacobus W.A. Burger9 Posterior Pelvic Exenteration 85Werner Hohenberger, Maximilian Brunner, and Susanne Merkel10 Total Pelvic Exenteration 90Satish K. Warrier, Andrew C. Lynch, and Alexander G. Heriot11 Extended Exenterative Resections Involving Bone 97Timothy Chittleborough, Gordon Beadel, and Frank Frizelle12 Exenterative Resections Involving Vascular and Pelvic Sidewall Structures 110Brian K. Bednarski and George J. Chang13 Extended Exenterative Resections for Recurrent Neoplasm 120Peter Sagar14 Pelvic Exenteration in the Setting of Peritoneal Disease 127Niels Kok, Arend Aalbers, and Geerard Beets15 Minimally Invasive Pelvic Exenteration 132Danielle Collins, Christos Kontovounisios, Shahnawaz Rasheed, and Paris Tekkis16 Stoma Considerations Following Exenteration 138Gabrielle H. van Ramshorst and Jurriaan B. Tuynman17 Reconstructive Techniques Following Pelvic Exenteration 149Dimitrios Patsouras, Alexis Schizas, and Mark George18 Minimizing Morbidity from Pelvic Exenteration 158Meara Dean, Alex Colquhoun, Peter Featherstone, Nicola S. Fearnhead, and R. Justin Davies19 Crisis Management 170Henrik Kidmose Christensen, Mette Møller Sørensen, and Victor Jilbert Verwaal20 Quality of Life and Patient-Reported Outcome Measures Following Pelvic Exenteration 177Daniel Steffens, Cherry Koh, and Michael Solomon21 Adjuvant Therapy Options after Pelvic Exenteration for Advanced Rectal Cancer 194Ka On Lam, Jeremy Yip, and Wai Lun Law22 Adjuvant Therapy Options after Pelvic Exenteration for Gynecological Malignancy 205Nisha Jagasia23 Adjuvant Therapy Options for Urological Neoplasms 214Gregory J. Nason, Clare O’Connell, and Paul K. Hegarty24 The Role of Re-irradiation for Locally Recurrent Rectal Cancer 223Johannes H.W. de Wilt and Jacobus W.A. Burger25 Palliative Pelvic Exenteration 230Hidde M. Kroon and Tarik Sammour26 Outcomes of Pelvic Exenteration for Locally Advanced and Recurrent Rectal Cancer 243Awad M. Jarrar and Scott R. Steele27 Outcomes Following Exenteration for Urological Neoplasms 255Frank McDermott, Ian Daniels, Neil Smart, and John McGrath28 Outcomes Following Exenteration for Gynecological Neoplasms 265Päivi Kannisto, Fredrik Liedberg, and Marie-Louise Lydrup29 Mesenchymal and Non-Epithelial Tumors of the Pelvis 283Eugenia Schwarzkopf and Patrick BolandIndex 298

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