Volume EditorKazuhiro Yamaguchi, MD, PhDDepartment of Respiratory Medicine, Tokyo Medical University, Tokyo, Japan Division of Respiratory Medicine, Tohto Clinic, Kenko-Igaku Association, Tokyo, Japan​Series EditorsHiroyuki Nakamura, Department of Respiratory Medicine, Tokyo Medical University, Ibaraki Medical Center, Ibaraki, JapanKazutetsu Aoshiba, Department of Respiratory Medicine, Tokyo Medical University, Ibaraki Medical Center, Ibaraki, Japan​

• Part I Respiratory control system.- 1.Anatomy and physiology of respiratory control system.- 2.Anatomy and physiology of chemical regulatory mechanisms in respiration.- 3.Coordination of swallowing and breathing.- Part IIUpper airway.- 4.Anatomy and function of upper airway during sleep.- 5.Instability of upper airway during anesthesia and sedation.- Part III Lower airway.- 6.Convective and Diffusive Mixing in Lower and Acinar Airways.- 7.Radiological evaluation of lower airway dimensions deciding ventilatory dynamics.- 8.Functional properties of lower airway estimated by oscillometry.- Part IV Acinus.- 9.Inhomogeneous distribution of ventilation-perfusion (VA/Q) and diffusing capacity-perfusion (D/Q) in the lung.- 10.Physiological Basis of Effective Alveolar-Arterial O2 Difference (AaDO2) and Effective Physiological Dead Space (VD/VT).- 11.Oxygen transport from air to tissues as an integrated system.- Part V Alveolar wall.- 12.Pathophysiological and clinicalimplication of diffusing capacity for CO (DLco) and Krogh factor (Kco).- 13.Basic perspective of simultaneous measurement of DLCO and DLNO.- 14.Reference equations for simultaneously measured DLCO and DLNO.- 15.Differential diagnosis based on newly developed indicator of DLNO/DLCO.- 16.Clinical significance of simultaneous measurements of DLCO and DLNO: Can DLCO and DLNO differentiate various kinds of lung diseases?.