Häftad, Engelska, 2026

Structural Biology of Ubiquitination

From Mechanisms to Interventions

Av Navaneet Chaturvedi, Vijay Kumar

2719 kr

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Beskrivning

Structural Biology of Ubiquitination: From Mechanisms to Interventions provides an in-depth exploration of the structural and biophysical principles governing ubiquitination and their implications in diseases such as cancer and neurodegeneration. The book seamlessly integrates experimental insights with advanced computational methods, including AI-driven drug discovery, molecular modeling, and biophysical simulations, offering a comprehensive toolkit for researchers and clinicians. By bridging fundamental science with translational applications, the book empowers readers to design targeted therapeutics, understand disease mechanisms at the molecular level, and accelerate progress toward personalized medicine.

Provides structural insights into ubiquitination pathways and their roles in diseases such as cancer and neurodegeneration
Utilizes computational and AI-driven approaches to advance drug discovery
Highlights the therapeutic relevance of the ubiquitin-proteasome system
Bridges experimental and computational research to support precision medicine

Produktinformation

Utgivningsdatum: 2026-11-25
Mått: 191 x 235 x undefined mm
Vikt: 450 g
Format: Häftad
Språk: Engelska
Antal sidor: 350
Förlag: Elsevier Science
ISBN: 9780443449741

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Mer information

Navaneet Chaturvedi is an assistant professor at the Amity Institute of Biotechnology, Amity University, Noida, India. He has built a solid foundation and essential skills for a research-intensive role. With extensive experience, Dr. Chaturvedi is eager to contribute to the vibrant research community. His work spans institutions worldwide, including Tel Aviv University, IIT BHU, University of Information Science & Tech North Macedonia, University of Leicester, and PharmCADD in South Korea, enabling collaboration with multidisciplinary teams and fostering innovation. His expertise includes molecular dynamics simulation, molecular docking, free energy calculations, machine learning, protein folding, and computer-aided drug design. Dr. Chaturvedi has a growing portfolio of research and review articles and book chapters published in leading international journals and publishers. Prof. Vijay Kumar is a distinguished faculty member and researcher specializing in Structural biology, Protein chemistry and neurosciences. He holds the position of Professor of the Department of Biotechnology, Anand School of Engineering and Technology, Sharda University, Agra. Prof. Kumar is internationally recognized and ranks among the top 2% of most cited scientists according to the STANFORD list. He earned his PhD in Biophysics from AIIMS, New Delhi, and completed a postdoctoral fellowship at UMass Medical School, focusing on folding and aggregation of proteins such as SOD1 and TDP-43 implicated in motor neuron disease, ALS, and FTD. He also served as Principal Investigator under the DST-SERB Young Scientist Scheme at Jamia Millia Islamia. His current research focuses on protein folding, misfolding, and aggregation, and the role of toxic RNA species in neurodegenerative diseases. He is a member of the Protein Society, Indian Biophysical Society, Indian Academy of Neurosciences, and the International Society for Neurochemistry. He has held fellowships from CSIR, India and a DAAD fellowship in Germany.

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