Stem Cell-Derived Exosomes and Microvesicles

Clinical Applications

Inbunden, Engelska, 2025

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This book is an essential resource on the technologies and applications of exosomes and extracellular microvesicles derived from stem cells. Divided into three parts, the book covers the biology of stem cell-derived extracellular vesicles; isolation, characterization, and manufacture of exosomes and extracellular vesicles from stem cells; and exosomes and extracellular vesicle therapy. Taken as a whole, readers will learn how exosomes and extracellular vesicles are produced for clinical use. This is an ideal book for clinical researchers, cell and stem cell scientists, corporate leaders, and scientific entrepreneurs, as well as undergraduate and graduate students studying medicine, the biological sciences, and biotechnology.

Produktinformation

Utgivningsdatum2025-06-25
Mått155 x 235 x 15 mm
Vikt422 g
FormatInbunden
SpråkEngelska
SerieStem Cells in Clinical Applications
Antal sidor158
FörlagSpringer International Publishing AG
ISBN9783031906978

Tillhör följande kategorier

Biokemisk teknik inom Naturvetenskap och teknik
Biomedicinsk teknik inom Medicin
Regenerativ medicin inom Medicin
Cellbiologi inom Naturvetenskap och teknik

Phuc Van Pham received his Ph.D. in Human Physiology from Vietnam National University Ho Chi Minh City, Viet Nam. He is currently a Professor of Biology at Vietnam National University and Acting Director of the Laboratory of Stem Cell Research and Application. He is a longstanding lecturer and translational scientist at the University, and is a member of several societies and journal editorial boards focused on stem cells. Dr. Pham and his colleagues have established one of the first multidisciplinary stem cell centers in Viet Nam, and he has successfully launched an array of technologies in stem cell isolations. His research interests include stem cell isolation, stem cell therapy, mesenchymal stem cells, cancer stem cells, immunotherapy and regenerative medicine and he has published extensively in these areas.Dr Sharmila Fagoonee is a Researcher at the Institute of Biostructure and Bioimaging of the Italian National Research Council (CNR) in Turin, Italy. After her B.Sc. (hons) degree in Biology at the University of Mauritius and M.Sc. degree in Cellular Biology at Université Victor Segalen, Bordeaux, France, she got her Ph.D. in Cell and Molecular Biology at the University of Turin, Italy. As a CNR researcher, she has investigated the differentiative capacity of murine pluripotent spermatogonial stem cells into functional hepatocytes both in vitro and in vivo. She is currently studying new therapies and biomarkers for chronic liver diseases as well as the role of the RNA binding proteins in hepatic and intestinal pathogenesis. She has also been coordinator and lecturer of the Master’s course in Stem Cells, Regenerative Medicine and Cell Factory Management at the University of Turin, and is active as Editorial Board member as well as Reviewer of several scientific journals.

An overview of extracellular vesicles.- Isolation of exosomes from cell culture supernatants.- Quality control of extracellular vesicles derived from stem cells for clinical applications.- Preservation of Extracellular Vesicles.- Manufacturing and Quality Control of Mesenchymal Stem Cell-Derived Exosomes for Clinical Application.- New advances in stem cell-derived extracellular vesicle functionalization technology.- Mesenchymal stem cells derived extracellular vesicles in therapeutic applications.- Potentiality of stem cell-derived extracellular vesicles in the setting of metabolic-dysfunction associated steatotic liver disease (MASLD).- Current applications of endothelial progenitor cells derived extracellular vesicles: from animals to bedside.