Del i serien Methods in Molecular Biology

Statistical Human Genetics

Methods and Protocols

Inbunden, Engelska, 2012

AvRobert C. Elston,Jaya M. Satagopan,Shuying Sun

2 139 kr

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Recent advances in genetics over the last quarter of a century, especially in molecular techniques, have dramatically reduced the cost of determining genetic markers and hence opened up a field of research that is increasingly helping to detect, prevent and/or cure many diseases that afflict humans.

Produktinformation

Utgivningsdatum2012-02-04
Mått178 x 254 x 36 mm
Vikt1 210 g
FormatInbunden
SpråkEngelska
SerieMethods in Molecular Biology
Antal sidor564
Upplaga2012
FörlagHumana Press Inc.
ISBN9781617795541

Tillhör följande kategorier

Medicinsk genetik inom Medicin
Epidemiologi och medicinsk statistik inom Medicin

Genetic Terminology.-Identification of Genotype Errors.-Detecting Pedigree Relationship Errors.-Identifying Cryptic Relationships.-Estimating Allele Frequencies.-Testing Departure from Hardy-Weinberg Proportions.-Estimating Disequilibrium Coefficients.-Detecting Familial Aggregation.-Estimating Heritability from Twin Studies.-Estimating Heritability from Nuclear Family and Pedigree Data.-Correcting for Ascertainment.-Segregation Analysis using the Unified Model.-Design Considerations For Genetic Linkage And Association Studies.-Model-based Linkage Analysis of a Quantitative Trait.-Model-based Linkage Analysis of a Binary Trait.-Model-free Linkage Analysis of a Quantitative Trait.-Model-free Linkage Analysis of a Binary Trait.-Single Marker Association Analysis for Unrelated Samples.-Single Marker Family-based Association Analysis Conditional on Parental Information.-Single Marker Family-based Association Analysis not Conditional on Parental Information.-Allowing for Population Stratification in Association Analysis.-Haplotype Inference.-Multi-SNP Haplotype Analysis Methods for Association Analysis.-Detecting Rare Variants.-The Analysis of Ethnic Mixtures.-IDENTIFYING GENE INTERACTION NETWORKS.-Structural Equation Modeling.-Genotype Calling for the Affymetrix Platform.-Genotype Calling for the Illumina Platform.-Comparison of Requirements and Capabilities of Major Multipurpose Software Packages.