Del i serien Methods in Molecular Biology

Statistical Human Genetics

Methods and Protocols

Häftad, Engelska, 2016

AvRobert C. Elston,Jaya M. Satagopan,Shuying Sun

2 089 kr

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Recent advances in genetics over the last quarter of a century, especially in molecular techniques, have dramatically reduced the cost of determining genetic markers and hence opened up a field of research that is increasingly helping to detect, prevent and/or cure many diseases that afflict humans.

Produktinformation

Utgivningsdatum2016-08-23
Mått178 x 254 x undefined mm
FormatHäftad
SpråkEngelska
SerieMethods in Molecular Biology
Antal sidor564
FörlagHumana Press Inc.
ISBN9781493958955

Tillhör följande kategorier

Medicinsk genetik inom Medicin
Matematisk statistik inom Naturvetenskap och teknik
Biovetenskap inom Naturvetenskap och teknik

Genetic Terminology.-Identification of Genotype Errors.-Detecting Pedigree Relationship Errors.-Identifying Cryptic Relationships.-Estimating Allele Frequencies.-Testing Departure from Hardy-Weinberg Proportions.-Estimating Disequilibrium Coefficients.-Detecting Familial Aggregation.-Estimating Heritability from Twin Studies.-Estimating Heritability from Nuclear Family and Pedigree Data.-Correcting for Ascertainment.-Segregation Analysis using the Unified Model.-Design Considerations For Genetic Linkage And Association Studies.-Model-based Linkage Analysis of a Quantitative Trait.-Model-based Linkage Analysis of a Binary Trait.-Model-free Linkage Analysis of a Quantitative Trait.-Model-free Linkage Analysis of a Binary Trait.-Single Marker Association Analysis for Unrelated Samples.-Single Marker Family-based Association Analysis Conditional on Parental Information.-Single Marker Family-based Association Analysis not Conditional on Parental Information.-Allowing for Population Stratification in Association Analysis.-Haplotype Inference.-Multi-SNP Haplotype Analysis Methods for Association Analysis.-Detecting Rare Variants.-The Analysis of Ethnic Mixtures.-IDENTIFYING GENE INTERACTION NETWORKS.-Structural Equation Modeling.-Genotype Calling for the Affymetrix Platform.-Genotype Calling for the Illumina Platform.-Comparison of Requirements and Capabilities of Major Multipurpose Software Packages.