Statistical Aspects Of The Design And Analysis Of Clinical Trials

• An introduction to clinical trials; treatment allocation, the size of trials and reporting results; monitoring trial progress - outcome measures, compliance, dropouts and interim analyses; basic analyses of clinical trials, the generalized linear model and the economic evaluation of trials; simple approaches to the analysis of longitudinal data from clinical trials; models for non-normal longitudinal data from clinical trials; survival analysis; Bayesian methods; meta-analysis.

"... given a keen amateur interest and an ability to skip the occasional rather daunting-looking equation this book is surprisingly accessible ... There's an introductory chapter containing an excellent historical overview." Transactions of Royal Society of Tropical Medicine and Hygiene, 2001