Spontaneous Pathology of the Laboratory Non-human Primate

Dr. Bradley has been with Charles River since 1998 where she is the senior director of pathology. In this capacity she leads a team of veterinary pathologists and pathology analysts. She has specialist interest and provides consultancy services in neuropathology, non-human primate pathology, medical devices, and cellular therapy products (human and animal stem cells). She is an experienced study pathologist for acute, long term reproductive toxicology, tumorigenicity, oncogenicity, microautoradiography, target animal safety and carcinogenicity studies. She has authored over 700 GLP or GMP compliant toxicological peer reviewed pathology and photomicroscopy reports. She is the GLP and GMP Study Director as well as the Quality Control Manager for GMP pathology services. Dr. Chilton has been with Charles River since 2007 where she is the senior veterinary pathologist. She has specialist interest and provides consultancy services in neuropathology, non-human primate and comparative pathology. She has authored numerous GLP and investigative toxicological reports and is currently the neuropathology liaison to The National Chimpanzee Brain Resource (NCBR), George Washington University, Washington DC and staff pathologist for the Alamogordo Primate Facility, Alamogordo, NM. Ms. Mahler is a Pathology Associate with over 32 years of experience as a certified histologist (HT) in the areas of histology, animal necropsy, and digital photomicroscopy. Since 2006, she has served as the illustrations editor for the journal Toxicologic Pathology. Past illustrative editorship roles include associate editor of Pathology of the Mouse, edited by Dr Robert R. Maronpot.

• 1. Introduction to 1st Edition2. Choice of Primate species3. Regulatory issues in the use of primates4. Infectious Diseases5. Clinical Examination6. Salivary glands7. Oral Cavity8. Esophagus and Stomach9. Small and Large Intestine10. Liver11. Exocrine Pancreas12. Kidney13. Urinary bladder, ureter, urethra14. Brain15. Spinal Cord and Nerves16. Eye and associated glands17. Skeletal Muscle18. Bone and Joints19. Skin and subcutis20. Specialized sebaceous glands21. Mammary Gland22. Respiratory tract23. Immune System24. Bone Marrow25. Female Reproductive Tract26. Testis27. Male sex glands28. Heart29. Blood Vessels30. Thyroid31. Parathyroid32. Pituitary33. Adrenal34. Endocrine Pancreas35. Hematology

“[A] reliable resource of consolidated references for pathologic processes in non-human primates,... a worthy objective as there are few dedicated pathology books in this arena.... This book is for pathologists working on primates in safety assessment studies and diagnostic veterinary pathologists working on non-human primates…. [and] would also be an asset for pathology residents and veterinary students seeking careers in laboratory animal medicine or laboratory animal pathology…. The systems chapters are the best aspect of the book. They provide good detail on pathologic processes based on organ system…. Overall, this is a useful book that consolidates knowledge from scattered resources on non-human primate pathology. Pathologists, residents, and students can use this book as a good starting point for disease investigation.” --©Doody’s Review Service, 2024, Jonathan Samuelson, DVM MS (University of Illinois College of Veterinary Medicine)