Del i serien Biotechnology: Pharmaceutical Aspects

Solvent Systems and Their Selection in Pharmaceutics and Biopharmaceutics

Inbunden, Engelska, 2007

AvPatrick Augustijns,Marcus Brewster

3 029 kr

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Solvent Systems and Their Selection in Pharmaceutics and Biopharmaceutics

Produktinformation

Utgivningsdatum2007-06-08
Mått178 x 254 x 34 mm
Vikt1 080 g
FormatInbunden
SpråkEngelska
SerieBiotechnology: Pharmaceutical Aspects
Antal sidor462
FörlagSpringer-Verlag New York Inc.
ISBN9780387691497

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Tillverkningsteknik inom Naturvetenskap och teknik

Principles of Solubility.- Ionic Equilibria and the pH Dependence of Solubility.- Solvent Systems for Crystallization and Polymorph Selection.- Solubility Issues in Early Discovery and HTS.- Practical Aspects of Solubility Determination in Pharmaceutical Preformulation.- Biorelevant Dissolution Media.- Selection of Solvent Systems for Membrane-, Cell- and Tissue-Based Permeability Assessment.- The Use of Solubilizing Excipients and Approaches to Generate Toxicology Vehicles for Contemporary Drug Pipelines.- Solubilizing Vehicles for Oral Formulation Development.- Solubilizing Systems for Parenteral Formulation Development—Small Molecules.- Aqueous Solubilizing Systems for Parenteral Formulation Development—Proteins.- Non-Aqueous Systems for Formulation Development—Proteins.- Pharmaceutical Solvents as Vehicles for Topical Dosage Forms.- Pharmaceutical Solvents for Pulmonary Drug Delivery.

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