The five-volume set constitutes the thoroughly refereed proceedings of the 8th International Conference on Life System Modeling and Simulation, LSMS 2024, and of the 8th International Conference on Intelligent Computing for Sustainable Energy and Environment, ICSEE 2024, which were held during September 13-15, in Suzhou, China.The 34 papers presented were carefully reviewed and selected from over 496 submissions. The LSMS and ICSEE international conference series aim to bring together international researchers and practitioners in the fields of advanced methods for life system modeling and simulation, as well as advanced intelligent computing theory, methodologies, and engineering applications in achieving net zero across all sectors to tackle the global climate change challenge.