Darcy Shaw, DVM, MVSc, Diplomate ACVIM (Internal Medicine), Associate Professor, Department of Companion Animals, University of Prince Edward Island, Charlottetown, Prince Edward Island, Canada. Sherri Ihle, DVM, MVSc, Diplomate ACVIM (Internal Medicine), Associate Professor, Department of Companion Animals, University of Prince Edward Island, Charlottetown, Prince Edward Island, Canada.

• Section I. Opening Scenarios Case 1. Episodic weakness in a Doberman pinscherCase 2. Acute collapse in a mixed-breed dogCase 3. Epistaxis in a NewfoundlandCase 4. Dyspnea in a domestic shorthaired catCase 5. Coughing in a miniature dachshundCase 6. Depression and ataxia in a mixed-breed dogCase 7. Increased urination in a miniature poodleCase 8. Increased urination and hematuria in a German shepherdCase 9. Intermittent diarrhea in a mixed-breed dogCase 10. Anorexia and weakness in a Great DaneCase 11. Seizures in a miniature schnauzerCase 12. Vomiting and lethargy in a golden retrieverSection II. History and Physical ExaminationSection III. Diagnostic TestsSection IV. Diagnosis ListSection V. TreatmentSection VI. Case Summaries and Explanations