Silk-Based Biomaterials for Tissue Engineering, Regenerative and Precision Medicine

Häftad, Engelska, 2023

Av Subhas C. Kundu, Rui L. Reis, Subhas C Kundu, Rui L Reis

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Silk-based Biomaterials for Tissue Engineering, Regenerative and Precision Medicine, Second Edition is a must-have reference, providing comprehensive coverage of silk-based biomaterials and their importance in translational uses and biomedicine. This new edition considers the progress made in the past eight years, featuring many new chapters, including a discussion of cutting-edge fabrication methods and techniques, new and improved blends/composites, and an expanded range of applications in tissue engineering, regenerative and precision medicine. The book holistically reviews the types, structure and properties, processing methods, and specific biomedical applications for silk-based biomaterials.

This will be a vital resource for materials and tissue engineering scientists, R&D departments in industry and academia, and academics interested in biomaterials, regenerative, and precision medicine.

Covers all key silk biomaterial types, including mulberry, Bombyx mori and nonmulberry/wild silk protein fibroins, sericins and spider silk, as well as their composite blends and various structures and scaffold platforms
Describes the cutting-edge processing techniques for each silk type, from traditional to nonconventional methods, such as using ionic liquids and engineering nanofibers and other biomedical matrices
Explores a range of applications in tissue engineering and regenerative and precision medicine, including bioprinting, bioelectronics and medical devices

Produktinformation

Utgivningsdatum2023-12-11
Mått152 x 229 x undefined mm
Vikt1 000 g
FormatHäftad
SpråkEngelska
SerieWoodhead Publishing Series in Biomaterials
Antal sidor906
Upplaga2
FörlagElsevier Science
ISBN9780323960175

Tillhör följande kategorier

Biokemisk teknik inom Naturvetenskap och teknik
Tillverkningsteknik inom Naturvetenskap och teknik
Biomedicinsk teknik inom Medicin
Regenerativ medicin inom Medicin
Maskinteknik och material inom Naturvetenskap och teknik

Subhas C. Kundu, PhD, is a Research Coordinator and former European Research Area Chair and Professor at the 3B´s Research Group, I3Bs – Institute on Biomaterials, Biodegradables and Biomimetics of the University of Minho, Portugal. His research interests include silk biomaterial matrices for biomedical applications, including 3D in vitro cancer models for investigating tumour growth and progression. In addition, he is using natural-based biomaterials for 3D cancer modelling and drug screening. Rui L. Reis, PhD, DSc, Hon. Causa MD, Hon Causa PhD, FBSE, FTERM, Dean of I3Bs - Institute on Biomaterials, Biodegradables and Biomimetics, Founding Director of the 3B’s Research Group, and Director of the PT Government ICVS/3B´s Associate Laboratory. He is the CEO of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine. He was the Global President of the Tissue Engineering and Regenerative Medicine International Society (TEMIS) and the former editor-in-chief of the Journal of Tissue Engineering and Regenerative Medicine. He received several major international awards and is the Associated Editor of PNAS Nexus. He is the chair of the Fellows of all the international societies on biomaterials sciences and engineering (FBSE). His research interest is tissue engineering, regenerative medicine, biomaterials and, increasingly, the development of 3D tissue-engineered disease models for the next generation of high-throughput predictive clinical tools, namely using living optical fibres based on the combination of living cells and hydrogels for the better understanding and optimizing of biomaterial/cell interactions.

1. Historical Silk Biomaterials2. Processing of Bombyx mori silk for use in biomedical and regenerative applications3. Cellular interaction with sericin: A basis for non-communicable and infectious diseases4. Tunable silk-based matrices using ionic liquids and their biomedical applications5. Biodegradability of silk biomaterials6. Engineering enzymatic and photo-crosslinked silk-based hydrogels for regenerative medicine7. Vascularization in porous silk fibroin as therapeutic biomaterials8. Structure and properties of spider and silkworm silk for tissue engineering, scaffolds and medicine9. Recent trends in controlled drug delivery based on silk platforms10. Silk for cardiac tissue engineering11. Silk proteins for bioelectronic devices in healthcare 12. Silk optics and electronics13. Silk biomaterials for tendon and tendon-to-bone enthesis tissue engineering14. Spider silks and their blends as biomaterials: Recent advances and future opportunities15. Silk fibroin nanofibers and blends for skin tissue engineering applications16. 3D Bioprinting of Articular Cartilage using Silk Fibroin-Gelatin Bioink17. Artificial silk fibers as biomaterials and their applications in biomedicine18. Translation of a silk-based medical device from bench to bedside19. Immune responses to silk proteins in vitro and in vivo: Lessons learnt20. Assembling silk into nanomedicines21. Silk scaffolds for dental tissue engineering (subject to change)22. 3D bioprinting using silk biomaterial ink: Where we are trying to move?23. Non-mulberry silk based biomaterials: Biomedical applications, current status and future perspective24. Silk protein: An emerging biomaterial for tumor modeling25. Microfibrillated silks and their potential applications26. Trends in silk biomaterials: technological advances and future strategies27. Silk fibroin smart hydrogels: Recent progress in tissue engineering and regenerative medicine28. Microfluidic Engineering of Silk Fibroin Biomaterial