Yao He is a professor at Institute of Functional Nano&Soft Materials (FUNSOM), Soochow University, China. He received his bachelor degree (2003) in Chemistry from Fudan University, China, and continued the Master and Ph.D. studies at the same university (2003-2007). He was a visiting scholar of the joint program at Shanghai Institute of Applied Physics, Chinese Academy of Sciences (2005-2007). Afterwards, he worked at the City University of Hong Kong, HKSAR, China, as a research fellow. He became an associate professor (2009) and was promoted to full professor (2011) at FUNSOM, Soochow University. His research interests focus on the development of silicon nanotechnology for biological and biomedical applications, particularly in bioimaging, biosensing, and cancer therapy, with the aim of providing promising tools for early diagnosis and treatment of diseases. Because of his original research on silicon nano-biotechnology, Prof. He received the Chinese Chemical Society Award for Young Scientists in 2012, and the National Science and Technology Leading Talent Award in 2012. Moreover, He served as the chief scientist of the “youth 973” project (National Key Scientific Research Projects, China) in 2013 on systematic exploration of silicon nano-biotechnology.Yuanyuan Su is an associate professor at Institute of Functional Nano&Soft Materials (FUNSOM), Soochow University, China. She received her bachelor degree (2005) in Biochemistry, and Ph.D. degree (2010) in Biochemistry and Molecular Biology from Nanjing University, China. Afterwards, she worked at the Center of Super-Diamond and Advanced Films (COSDAF), City University of Hong Kong, HKSAR, China, as a senior research associate. In 2011, she joined Prof. He’s group and became an associate professor at FUNSOM, Soochow University. Her research interests are in nanomaterial-based disease therapy and nano-biosafety assessment.

• Introduction.- Silicon Nanostructures.- Silicon-Based Platform for Biosensing Applications.- Silicon-Based Nanoprobes for Bioimaging Applications.- Silicon-Based Nanoagents for Cancer Therapy.- Biosafety Assessment of Silicon Nanomaterials.- Outlook.