Signal Transduction and Smooth Muscle

Inbunden, Engelska, 2018

Av Mohamed Trebak, Scott Earley, USA) Trebak, Mohamed (Penn State College of Medicine, University Park, State College, USA) Earley, Scott (University of Nevada, Reno

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All hollow organs, such as blood vessels, the gastrointestinal tract, airways, male and female reproductive systems, and the urinary bladder are primarily composed of smooth muscle. Such organs regulate flow, propulsion and mixing of luminal contents and storage by the contraction and relaxation of smooth muscle cells. Smooth muscle cells respond to numerous inputs, including pressure, shear stress, intrinsic and extrinsic innervation, hormones and other circulating molecules, as well as autocrine and paracrine factors. This book is a review of smooth muscle cell regulation in the cardiovascular, reproductive, GI, and other organ systems with emphasis on calcium and receptor signaling.Key selling features:Focuses on smooth muscles of different typesDescribes ion channel signaling mechanismsReviews calcium and receptor signalingIncludes novel, cutting-edge methodologiesSummarizes studies of mice with genetically encoding sensors in smooth muscleChapter 9 of this book is freely available as a downloadable Open Access PDF at http://www.taylorfrancis.com under a Creative Commons Attribution (CC-BY) 4.0 license.

Produktinformation

Utgivningsdatum2018-09-11
Mått156 x 234 x 24 mm
Vikt857 g
FormatInbunden
SpråkEngelska
SerieMethods in Signal Transduction Series
Antal sidor412
FörlagTaylor & Francis Inc
ISBN9781498774222

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Fysiologi inom Medicin

Series PrefacePrefaceEditorsContributorsChapter 1 Elucidation of Vasopressin Signal Transduction Pathways in Vascular Smooth MuscleKenneth L. Byron and Lyubov I. BrueggemannChapter 2 Investigating Chloride Channels in Smooth MuscleHenry R. Askew Page and Iain A. GreenwoodChapter 3 Methods for the Isolation of and Study of Ca2+ Signaling in Arteriolar Smooth Muscle CellsWilliam F. JacksonChapter 4 Ion Channel Trafficking in Arterial Smooth Muscle Cells and Functional SignificanceM. Dennis Leo and Jonathan H. JaggarChapter 5 Total Internal Reflection Fluorescence Microscopy in Vascular Smooth MuscleMadeline Nieves-Cintrón, Sendoa Tajada, L. Fernando Santana, and Manuel F. NavedoChapter 6 T-Type Ca2+ Channels in Vascular Smooth Muscle: Properties, Regulation, and FunctionOsama F. Harraz, Ahmed M. Hashad, and Donald G. WelshChapter 7 Calcium Sensitization in Smooth Muscle Involving Regulation of Myosin Light Chain Phosphatase ActivityJustin A. MacDonald, Michael P. Walsh, and William C. ColeChapter 8 Approaches for Investigating the Functional Significance of Transient Receptor Potential Cation Channels in Smooth Muscle CellsHarry A. T. Pritchard, Paulo W. Pires, and Scott EarleyChapter 9 Mitochondria Structure and Position in the Local Control of Calcium Signals in Smooth Muscle CellsJohn G. McCarron, Christopher Saunter, Calum Wilson, John M. Girkin, and Susan ChalmersChapter 10 ORAI Channels in Vascular Smooth MuscleMaxime Guéguinou, Xuexin Zhang, Trayambak Pathak, Scott Emrich, Ryan Yoast, and Mohamed TrebakChapter 11 G Protein-Coupled Receptors in Airway Smooth Muscle Function and Obstructive Lung DiseaseTonio Pera and Raymond B. PennChapter 12 Brain-Derived Neurotrophic Factor in Airway Smooth Muscle: Contributions to AsthmaMichael Thompson, Rodney Britt Jr, Anne Roesler, Katelyn Cummings, Christina M. Pabelick, and Y. S. PrakashChapter 13 Antibody-Based Approaches for Protein Analysis of Smooth MusclesBrian A. Perrino and Yeming XieChapter 14 Role of Ion Channels in Urinary Bladder Smooth Muscle FunctionGeorgi V. PetkovChapter 15 Methods for Investigating the Regulation of Smooth Muscle Excitability by Interstitial CellsBernard T. Drumm and Kenton M. SandersChapter 16 Electrical Pacemaking in Lymphatic VesselsScott D. Zawieja, Jorge A. Castorena-Gonzalez, Kim H. T. To, Peichun Gui, Timothy Domeier, and Michael J. DavisChapter 17 NADPH Oxidase, Redox Signaling, and Vascular Smooth Muscle FunctionDaniel S. de Jesus, Eugenia Cifuentes-Pagano, Sanghamitra Sahoo, and Patrick J. PaganoIndex