Professor Alistair Burns, University of Manchester, UK, Professor of Old Age Psychiatry, Director of Research and Development for the South Manchester University Hospitals' Trust, Editor of the International Journal of Geriatric Psychiatry, Chair of the UK Alzheimer's Society Medical and Scientific Advisory Committee Panel, Immediate past-president of the International Psychogeriatrics Association (IPA)  Dr. Bengt Winblad, Karolinska Institute, Stockholm, Sweden, Professor of Geriatric Medicine, IPA Board Member, member of the Nobel Assembly for the Prize of Medicine and Physiology at the Karolinska Institute, Research Director of the Stockholm Gerontology Research Center.

• List of contributors. Introduction.PART 1: INTRODUCTORY.Chapter 1: Assessment and Diagnosis of Severe Dementia (Paul Newhouse and Joseph Lasek).Chapter 2: Neurochemistry of Severe Dementia (Sally I. Sharp, Paul T. Francis and Clive G. Ballard).Chapter 3: The Molecular Pathology of Severe Dementia (Clive Holmes).PART 2: CLINICAL FEATURES OF SEVERE DEMENTIA.Chapter 4: Cognitive Functions in Severe Dementia (Judith Saxton and François Boller).Chapter 5: Behavioural and Psychological Symptons of Dementia – Agitation (E. Jane Byrne and Deborah Collins).Chapter 6: Depression in Severe Dementia (Kate Bielinski and Brian Lawlor).Chapter 7: Physical Aspects of Severe Alzheimer’s Disease (Bruno Vellas).Chapter 8: Clinical Features of Severe Dementia: Staging (Barry Reisberg, Jerzy Wegiel, Emile Franssen, Sridhar Kadiyala, Stefanie Auer, Liduïn Souren, Marwan Sabbagh and James Golomb).Chapter 9: Clinical Features of Severe Dementia: Function (Serge Gauthier).PART 3: MANAGEMENT.Chapter 10: Drug Treatment: Memantine (Anton P. Porsteinsson and Pierre N. Tariot).Chapter 11: Drug Treatment: Cholinesterase Inhibitors (Michael Woodward and Howard Feldman).Chapter 12: Drug Treatment: Treatment of Behavioural and Psychological Symptoms of Dementia with Neuroleptics (Peter Paul De Deyn).Chapter 13: Non-pharmacological Treatment of Severe Dementia: An Overview (Ross Overshott and Alistair Burns).Chapter 14: Non-pharmacological Treatment of Severe Dementia: the Seattle Protocols (Rebecca G. Logsdon, Linda Teri and Sue M. McCurry).Chapter 15: Care by Families for Late Stage Dementia (Steven H. Zarit and Joseph E. Gaugler).Chapter 16: Person-centred Care for People with Severe Dementia (Murna Downs, Neil Small and Katherine Froggatt).Chapter 17: Palliative Care in Patients with Severe Dementia (Raymond Koopmans, H. Roeline W. Pasman and Jenny T. van der Steen).Chapter 18: Narrative Ethics and Ethical Narratives in Dementia (Clive Baldwin).Chapter 19: Health Economics of Severe Dementia (Anders Wimo and Bengt Winblad).Index.

"This is an excellent book for those interested in the care of patients with sever dementia." (Doody's Health Services)

Professor Alistair Burns, University of Manchester, UK, Professor of Old Age Psychiatry, Director of Research and Development for the South Manchester University Hospitals' Trust, Editor of the International Journal of Geriatric Psychiatry, Chair of the UK Alzheimer's Society Medical and Scientific Advisory Committee Panel, Immediate past-president of the International Psychogeriatrics Association (IPA)  Dr. Bengt Winblad, Karolinska Institute, Stockholm, Sweden, Professor of Geriatric Medicine, IPA Board Member, member of the Nobel Assembly for the Prize of Medicine and Physiology at the Karolinska Institute, Research Director of the Stockholm Gerontology Research Center.

• List of contributors. Introduction.PART 1: INTRODUCTORY.Chapter 1: Assessment and Diagnosis of Severe Dementia (Paul Newhouse and Joseph Lasek).Chapter 2: Neurochemistry of Severe Dementia (Sally I. Sharp, Paul T. Francis and Clive G. Ballard).Chapter 3: The Molecular Pathology of Severe Dementia (Clive Holmes).PART 2: CLINICAL FEATURES OF SEVERE DEMENTIA.Chapter 4: Cognitive Functions in Severe Dementia (Judith Saxton and François Boller).Chapter 5: Behavioural and Psychological Symptons of Dementia – Agitation (E. Jane Byrne and Deborah Collins).Chapter 6: Depression in Severe Dementia (Kate Bielinski and Brian Lawlor).Chapter 7: Physical Aspects of Severe Alzheimer’s Disease (Bruno Vellas).Chapter 8: Clinical Features of Severe Dementia: Staging (Barry Reisberg, Jerzy Wegiel, Emile Franssen, Sridhar Kadiyala, Stefanie Auer, Liduïn Souren, Marwan Sabbagh and James Golomb).Chapter 9: Clinical Features of Severe Dementia: Function (Serge Gauthier).PART 3: MANAGEMENT.Chapter 10: Drug Treatment: Memantine (Anton P. Porsteinsson and Pierre N. Tariot).Chapter 11: Drug Treatment: Cholinesterase Inhibitors (Michael Woodward and Howard Feldman).Chapter 12: Drug Treatment: Treatment of Behavioural and Psychological Symptoms of Dementia with Neuroleptics (Peter Paul De Deyn).Chapter 13: Non-pharmacological Treatment of Severe Dementia: An Overview (Ross Overshott and Alistair Burns).Chapter 14: Non-pharmacological Treatment of Severe Dementia: the Seattle Protocols (Rebecca G. Logsdon, Linda Teri and Sue M. McCurry).Chapter 15: Care by Families for Late Stage Dementia (Steven H. Zarit and Joseph E. Gaugler).Chapter 16: Person-centred Care for People with Severe Dementia (Murna Downs, Neil Small and Katherine Froggatt).Chapter 17: Palliative Care in Patients with Severe Dementia (Raymond Koopmans, H. Roeline W. Pasman and Jenny T. van der Steen).Chapter 18: Narrative Ethics and Ethical Narratives in Dementia (Clive Baldwin).Chapter 19: Health Economics of Severe Dementia (Anders Wimo and Bengt Winblad).Index.

"This is an excellent book for those interested in the care of patients with sever dementia." (Doody's Health Services)

Professor Alistair Burns, University of Manchester, UK, Professor of Old Age Psychiatry, Director of Research and Development for the South Manchester University Hospitals' Trust, Editor of the International Journal of Geriatric Psychiatry, Chair of the UK Alzheimer's Society Medical and Scientific Advisory Committee Panel, Immediate past-president of the International Psychogeriatrics Association (IPA)  Dr. Bengt Winblad, Karolinska Institute, Stockholm, Sweden, Professor of Geriatric Medicine, IPA Board Member, member of the Nobel Assembly for the Prize of Medicine and Physiology at the Karolinska Institute, Research Director of the Stockholm Gerontology Research Center.

• List of contributors. Introduction.PART 1: INTRODUCTORY.Chapter 1: Assessment and Diagnosis of Severe Dementia (Paul Newhouse and Joseph Lasek).Chapter 2: Neurochemistry of Severe Dementia (Sally I. Sharp, Paul T. Francis and Clive G. Ballard).Chapter 3: The Molecular Pathology of Severe Dementia (Clive Holmes).PART 2: CLINICAL FEATURES OF SEVERE DEMENTIA.Chapter 4: Cognitive Functions in Severe Dementia (Judith Saxton and François Boller).Chapter 5: Behavioural and Psychological Symptons of Dementia – Agitation (E. Jane Byrne and Deborah Collins).Chapter 6: Depression in Severe Dementia (Kate Bielinski and Brian Lawlor).Chapter 7: Physical Aspects of Severe Alzheimer’s Disease (Bruno Vellas).Chapter 8: Clinical Features of Severe Dementia: Staging (Barry Reisberg, Jerzy Wegiel, Emile Franssen, Sridhar Kadiyala, Stefanie Auer, Liduïn Souren, Marwan Sabbagh and James Golomb).Chapter 9: Clinical Features of Severe Dementia: Function (Serge Gauthier).PART 3: MANAGEMENT.Chapter 10: Drug Treatment: Memantine (Anton P. Porsteinsson and Pierre N. Tariot).Chapter 11: Drug Treatment: Cholinesterase Inhibitors (Michael Woodward and Howard Feldman).Chapter 12: Drug Treatment: Treatment of Behavioural and Psychological Symptoms of Dementia with Neuroleptics (Peter Paul De Deyn).Chapter 13: Non-pharmacological Treatment of Severe Dementia: An Overview (Ross Overshott and Alistair Burns).Chapter 14: Non-pharmacological Treatment of Severe Dementia: the Seattle Protocols (Rebecca G. Logsdon, Linda Teri and Sue M. McCurry).Chapter 15: Care by Families for Late Stage Dementia (Steven H. Zarit and Joseph E. Gaugler).Chapter 16: Person-centred Care for People with Severe Dementia (Murna Downs, Neil Small and Katherine Froggatt).Chapter 17: Palliative Care in Patients with Severe Dementia (Raymond Koopmans, H. Roeline W. Pasman and Jenny T. van der Steen).Chapter 18: Narrative Ethics and Ethical Narratives in Dementia (Clive Baldwin).Chapter 19: Health Economics of Severe Dementia (Anders Wimo and Bengt Winblad).Index.

"This is an excellent book for those interested in the care of patients with sever dementia." (Doody's Health Services)