Serum/Plasma Proteomics

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• Protocols for the Isolation of Platelets for Research and Contrast to Production of Platelet Concentrates for Transfusion.- Collection of plasma samples in areas with limited healthcare access.- Blood Collection Processing & Handling for Plasma and Serum Proteomics.- Preparation of cryoprecipitate and cryo-depleted plasma for proteomic research analysis.- High throughput proteome profiling of plasma and native plasma complexes using native chromatography.- High-throughput and in-depth proteomic profiling of 5 µL plasma and serum using TMTpro 16plex.- In depth data-independent acquisition proteomics of human plasma identifies low abundant proteins.- In-depth Blood Proteome Profiling by Extensive Fractionation and multiplexed quantitative mass spectrometry.- Early cancer biomarker discovery using DIA-MS proteomic analysis of EVs from peripheral blood.- Strategies to enrich, identify and characterize glycoproteome in blood plasma using Liquid Chromatography High Resolution Mass Spectrometry.- Proteome analysis of whole blood collected by volumetric absorptive microsampling.- Proteomic applications and considerations: from research to patient care.- Immunoaffinity mass spectrometry diagnostic tests for multi-biomarker assays.- Secretome profile of leukocyte-platelet rich fibrin (L-PRF) membranes.- Quantification of proteins in blood by absorptive microtiter plate-based affinity purification coupled to liquid chromatography-mass spectrometry.- Glycomics-assisted Glycoproteomics Enables Deep and Unbiased N-Glycoproteome Profiling of Complex Biological Specimens. -The Small Protein Enrichment Assay (SPEA) for analysis of low abundance peptide hormones in plasma.- In-depth proteomic analysis of blood circulating small extracellular vesicles.- Protocol for Plasma Extracellular Vesicle and Particle Isolation and Mass Spectrometry-based Proteomic Identification.- Analysis of ExtracellularVesicle and Contaminant Markers in Blood Derivatives Using Multiple Reaction Monitoring.- Generation of red blood cell nanovesicles as a delivery tool.- Progress in targeted mass spectrometry (parallel accumulation-serial fragmentation) and its application in plasma/serum proteomics.- Offline peptide fractionation and parallel reaction monitoring MS for the quantitation of low-abundance plasma proteins.- Profiling Serum Intact N-Glycopeptides Using Data-Independent Acquisition Mass Spectrometry.- Semi-automated lectin magnetic bead array (LeMBA) for translational serum glycoprotein biomarker discovery and validation.- Accessing antibody-reactivities in serum or plasma to (auto-)antigens using multiplexed bead-based protein immunoassays.- Absolute quantitative targeted proteomics assays for plasma proteins.- Rapid and quantitative enrichment of peptides from plasma for mass spectrometric analysis.- Comprehensive targeted lipidomic profilingfor research and clinical applications.- Multiplexed bead-based peptide immunoassays for the detection of antibody reactivities.- Array-based multiplex and high-throughput serology assays.- Bioinformatic tools and knowledgebases to assist generating targeted assays for plasma proteomics.- Use of Longitudinal Serum Analysis and Machine Learning to Develop a Classifier for Cancer Early Detection.