Self-assessment Q&A in Clinical Laboratory Science, III

Dr. Alan Wu is a Professor of Laboratory Medicine at the University of California at San Francisco. He is the Co-Director of the Core Laboratory at the Zuckerberg San Francisco General Hospital. His research is focused on biomarkers of cardiovascular disease, clinical toxicology, and pharmacogenomics. In this capacity, his clinical and research laboratory conducts testing for routine analytes in blood, urine and cerebral spinal fluid for electrolytes, metabolites, hormones, proteins, and biomarkers. His particular area of interest is in cardiac biomarkers for acute cardiac diseases. He received a B.S. in both Chemistry and Biology at Purdue University and a Ph.D. in Analytical Chemistry at the University of Illinois. He was a professor at the University of Texas and the University of Connecticut prior to his current position at UCSF.

• 1. Mass spectrometry2. Kidney markers3. Cancer markers4. Pregnancy5. Heavy metals and ICP-MS6. Protein electrophoresis7. Sepsis8. Molecular diagnostics for infectious diseases9. Clinical and forensic toxicology10. Point-of-care testing11. Point-of-care technology12. Cardiac markers13. Multiple myeloma14. Liquid biopsy15. Pharmacogenomics16. Pharmacokinetics and pharmacodynamics17. Reference ranges18. Regulations19. Hemolysis20. Icterus21. Lipemia22. Pre-analytical variables23. Bioinformatics24. Therapeutic drug monitoring25. Lab automation26. Transplant TDM27. Newborn screening28. Lab statistics29. Pediatric clinical chemistry30. Hematology31. Immunology32. Autoimmune33. Novel cardiovascular biomarkers34. Antimicrobial resistance testing35. Biomarkers of neurologic diseases36. HLA testing

"This is a great set of questions to test one's fund of basic clinical laboratory science knowledge. A word of caution - medicine does evolve and some of the answers may no longer be current. There are also occasional errors. If a reader doesn't think an answer is correct, they should research it and let the authors know the correct answer for the next edition." --Doody