Selection of the HPLC Method in Chemical Analysis

Häftad, Engelska, 2016

AvSerban C. Moldoveanu,Victor David,USA) Moldoveanu, Serban C. (Senior Principal Scientist, RJ Reynolds Tobacco Co., Winston-Salem, NC,Romania) David, Victor (Professor and Head of the Department of Analytical Chemistry, University of Bucharest

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Selection of the HPLC Method in Chemical Analysis serves as a practical guide to users of high-performance liquid chromatography and provides criteria for method selection, development, and validation.

High-performance liquid chromatography (HPLC) is the most common analytical technique currently practiced in chemistry. However, the process of finding the appropriate information for a particular analytical project requires significant effort and pre-existent knowledge in the field. Further, sorting through the wealth of published data and literature takes both time and effort away from the critical aspects of HPLC method selection.

For the first time, a systematic approach for sorting through the available information and reviewing critically the up-to-date progress in HPLC for selecting a specific analysis is available in a single book. Selection of the HPLC Method in Chemical Analysis is an inclusive go-to reference for HPLC method selection, development, and validation.

Addresses the various aspects of practice and instrumentation needed to obtain reliable HPLC analysis results
Leads researchers to the best choice of an HPLC method from the overabundance of information existent in the field
Provides criteria for HPLC method selection, development, and validation
Authored by world-renowned HPLC experts who have more than 60 years of combined experience in the field

Produktinformation

Utgivningsdatum2016-11-15
Mått191 x 235 x 30 mm
Vikt1 220 g
FormatHäftad
SpråkEngelska
Antal sidor598
FörlagElsevier Science
ISBN9780128036846

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Dr. Serban C. Moldoveanu held several teaching positions at the University of Bucharest, Romania, until 1983, when he immigrated to the United States. There, he continued teaching at the university level for several years before focusing primarily on industrial research. He served as Senior Principal Scientist at R.J. Reynolds Tobacco Company and retired at the end of 2023. His research has centered on various aspects of chromatography, including method development for the analysis of natural products using GC/MS, HPLC, and LC/MS/MS. He has also investigated the pyrolysis of a variety of polymers and organic compounds. Dr. Moldoveanu has published more than 150 articles in peer-reviewed journals, 8 books with Elsevier, approximately 22 patents/patent applications, and several book chapters. He was honored with the Tobacco Science Research Conference Lifetime Achievement Award in 2012 and currently serves as an editor for three chemistry journals.Victor David was a Professor and Head of the Department of Analytical Chemistry, University of Bucharest, Romania. Recently retired, he remains Emeritus Professor at the same Department. His main field of research is separation science (theory and applications in various scientific domains). He is the author of more than 200 publications, including over 150 scientific papers in peer reviewed journals and 25 books and chapters. He is member of editorial board of Biomedical Chromatography, Molecules, Journal of Essential Oil-Bearing Plants and Revue Roumaine de Chimie.

1. Start of the Implementation of a New HPLC Method2. Short Overviews of Analytical Techniques Not Containing an Independent Separation Step3. Short Overviews of the Main Analytical Techniques Containing a Separation Step4. Basic Information Regarding the HPLC Techniques5. Properties of Analytes and Matrices Determining HPLC Selection6. General Aspects Regarding the HPLC Analytical Column7. RP-HPLC Analytical Columns8. Polar Analytical Columns9. Stationary Phases and Columns for Ion Exchange, Ion-Moderated, and Ligand Exchange Chromatography10. Stationary Phases and Columns for Chiral Chromatography11. Stationary Phases and Columns for Size Exclusion12. Stationary Phases and Columns for Immunoaffinity Type Separations13. Solvents, Buffers, and Additives Used in the Mobile Phase14. Gradient Elution15. The Practice of HPLC

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Serban C. Moldoveanu, Victor David, USA) Moldoveanu, Serban C. (Senior Principal Scientist, RJ Reynolds Tobacco Co., Winston-Salem, NC, Romania) David, Victor (Professor and Head of the Department of Analytical Chemistry, University of Bucharest, Serban Moldoveanu

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