The author explores the impact and role of global partnership sustainable development change initiatives in the context of various types of partnerships in making progress toward the United Nations Sustainable Development Goal (SDG) 17 and improving partnership performance. She contends that current partnership practices may hinder sustainable business benefits through a disregard for excellence and a lack of deeper knowledge of how partnerships can impact corporate and public value. She examines partnership types, trends, models, collaborative knowledge creation processes, activities, and patterns and describes how to formulate, integrate, implement, and monitor partnership performance. She discusses key areas that have been overlooked, current partnership performance trends and projections of change and transformation across sectors, and current guidelines for improving partnership performance. She addresses the definition of partnerships; cooperative value and knowledge creation and the challenges of collaborative governance performance in private-public and cross-sector partnerships; stakeholder tools and policies; examples of partnerships and the institutional factors and global partnership development challenges that contribute to success or failure; collective intelligence and regulatory practices; partnership intervention strategies through innovation, risk management, and governance mechanisms; and areas that have been overlooked in the pursuit of the objectives of sustainable development, including partnership performance and governance, the common good and cross-border partnerships among government, business, and society, and environmental, social, and governance investing.