Science of Flavonoids

Dr. Grotewold is an Associate Professor of Plant Biology at The Ohio State University. He received his Ph.D from the Instituto de Ingenieria Genetics y Bologia Molecular, University of Buenos Aires, Argentina in 1988. His research focuses on Regulation of Gene Expression; Function and Evolution of Myb Proteins; Plant Metabolic Engineering. Combining molecular, cellular, biochemical and genetic approaches, his laboratory investigates fundamental questions regarding the mechanisms by which plants control gene expression, and how transcription factors have impacted plant evolution and speciation. He has started to develop regulatory networks in Arabidopsis that should help explain how the 28,000+ Arabidopsis genes are expressed. In addition, he is utilizing his extensive knowledge on transcription factors for plant metabolic engineering.

• The Stereochemistry of Flavonoids.- Isolation and Identification of Flavonoids.- The Biosynthesis of Flavonoids.- The Regulation of Flavonoid Biosynthesis.- Transport of Flavonoids: From Cytosolic Synthesis to Vacuolar Accumulation.- Flavonoid Pigments as Tools in Molecular Genetics.- The Evolution of Flavonoids and Their Genes.- Flavonoids as Nutraceuticals.- Flavonoids as Signal Molecules: Targets of Flavonoid Action.