Safety and efficacy of radiopharmaceuticals 1987

• 1: Safety and Efficacy of Radiopharmaceuticals with Emphasis on Biological Products.- 1 Design and development of radiopharmaceuticals based on monoclonal antibodies.- 2 Newer Technetium-99m radiopharmaceuticals.- 3 Labelling methods with radioactive iodine.- 4 Labelling with Indium-111.- 5 Labelling methods with Technetium-99m.- 6 Animal models for the evaluation of radiopharmaceuticals.- 7 Models for safety testing of immunoreactive pharmaceuticals.- 8 A mouse tumour model for screening radiotracer uptake into primary neoplasms and metastatic disease.- 9 Monoclonal antibodies and their radionuclide conjugates: Practical and regulatory aspects.- 10 Specifications and quality control methods for labelled cells.- 11 Radiochemical purity determination of labelled proteins.- 12 Safety aspects of human use of labelled cells.- 13 The basis for preliminary clinical trials of monoclonal antibodies for diagnosis and therapy.- 2: Radiopharmacy / Radiation Hygiene.- 14 “Dose” validation — How do we garantee that the patient is given the prescribed activity.- 15 Daily Practice in radiopharmacy with special reference to therapy.- 16 Waste disposal.- 17 Tc-99 — A waste problem?.- 3: Legal aspects of the introduction of new radiopharmaceuticals.- 18 Report on the WHO workshop for administrators in the field of radiopharmaceuticals.- 19 Current trends in the requirement for safety and efficacy of new drugs.- 20 Relationship between industry, hospitals and authorities.- 21 Relationship between industry, hospitals and authorities.- 22 Relationship between industry, hospitals and authorities.- 4: Selected aspects of Good Radiopharmacy Practice.- 23 Design of a hospital system for production of radiopharmaceuticals (Quality Assurance programme for a labelled biological product).-24 New developments: Laboratory facilities / product quality.- 25 Process validation.- 26 The radiopharmacy as an information center.- 27 Current trends in the training and education of pharmasists in radiopharmacy.

' We feel this book is an essential addition to the library of nuclear medicine departments, and we would without hesitation recommend this book to libraries. ' P.J. Ell in the British Journal of Radiology, January 1989.