This book constitutes the refereed proceedings of the Second EAI International Conference on Safe, Secure, Ethical, Responsible Technologies and Emerging Applications, SAFER-TEA 2024, held in Dubai, United Arab Emirates, during December 9–10, 2024.The 17 full papers included in this book were carefully reviewed and selected from 50 submissions. They were organized in topical sections as follows: Networking and Security; Artificial Intelligence risks and regulations; Technologies and Social Impact; and Investigations.