Douglas S. Tyler, MD, MSHCT is a distinguished Professor of Surgery at the University of North Carolina, Chapel Hill, serving as the Associate Chair of Community Operations and Strategy and Director of Hillsborough Services in the Department of Surgery. His past roles include the John Woods Harris Distinguished Chair in Surgery at the University of Texas Medical Branch and Chairman of the Department of Surgery.

• SECTION I SURGICAL TRAINING AND QUALITY CONTROL1. Surgical Education: Past, Present, and Future2. Surgical Simulation and New Ways to Optimize Performance3. Certification of Surgeon Competence4. Preoperative Risk Assessment and Alterations in the COVID-19 Era5. Social Determinants of Health and Their Impact on Surgical Outcomes6. Critical Assessment of Surgical Outcomes and Health Services Research7. Surgical Quality Improvement Programs8. Patient-Reported Outcomes9. Safety in the Surgical Environment10. Advances and Training Considerations in Robotic Surgery11. Advances and Training Considerations in Laparoscopic Surgery12. Advances and Training Considerations in Endoscopy and Endoscopic Surgery13. Telehealth in Surgery14. Health Inequities and Disparities in Surgery15. Global Surgery16. Ethics and Professionalism in Surgery17. Surgeon Health: Ergonomics18. Surgeon Health and Well-BeingSECTION II PERIOPERATIVE MANAGEMENT19. Principles of Preoperative and Operative Surgery20. Anesthesiology Principles, Pain Management, and Sedation21. Optimizing Surgical Outcomes: Prehabilitation and Rehabilitation22. Enhanced Recovery After Surgery (ERAS): Evidence-Based Perioperative Pathways to Optimize Outcomes23. Wound Healing24. The Evolving Role of the Microbiome in Surgical Practice25. Surgical Site Infections26. Surgical Complications: Overview and Grading27. Surgery in the Geriatric Patient28. Surgery in the Pregnant Patient29. Surgical Considerations in the Transgender Patient30. Surgical Palliative Care31. Advanced Analytics and Artificial Intelligence Applications in SurgerySECTION III TRAUMA AND CRITICAL CARE32. The Inflammatory Response33. Shock, Electrolytes, and Fluid34. Metabolism and Nutrition in Surgical Patients35. Primary Soft Tissue Infections36. Management of Acute Trauma37. The Difficult Abdominal Wall38. Management of Vascular Trauma39. Management of Urologic Trauma40. Emergency Care of Musculoskeletal Injuries41. Emergency Care of Neurologic Injuries42. Management of Pediatric Trauma43. Burns44. The Outdoors-Venomous Bites and Stings and Environmental Exposure45. Management of Chronic Wounds46. Surgical Critical Care47. Moving Operating Room Procedures to the Intensive Care Unit48. The Surgeon’s Role in Disaster ManagementSECTION IV TRANSPLANTATION AND IMMUNOLOGY49. Transplantation Immunobiology and Immunosuppression50. Regenerative Medicine and Its Applications to Surgery51. Surgical Considerations in Transplant Patients Undergoing Nontransplant-Related Procedures and Operating in Patients With Portal Hypertension52. Kidney Transplantation53. Liver Transplantation54. Pancreas Transplantation55. Islet Transplantation56. Small Bowel Transplantation57. Heart Transplantation58. Lung Transplantation59. Soft Tissue TransplantationSECTION V SURGICAL ONCOLOGY60. Tumor Biology and Tumor Markers61. Tumor Immunology and Immunotherapy62. Surgical Considerations in Cancer Patients63. Melanoma and Cutaneous Malignancies64. Sarcomas of the Soft Tissues, Retroperitoneum, and Bone65. Gastrointestinal Stromal Tumors66. Benign Diseases of Head and Neck67. Head and Neck Cancer68. Diseases of the Breast69. Plastic Surgical Considerations in Cancer Surgery70. Peritoneal Malignancy and HIPEC71. Surgeon’s Approach to Lymphadenopathy72. The SpleenSECTION VI ENDOCRINE DISORDERS73. The Thyroid74. Parathyroid75. The Adrenal Glands76. Pancreatic Neuroendocrine Tumors77. Neuroendocrine Neoplasms (Carcinoid Tumors)78. The Multiple Endocrine Neoplasia SyndromesSECTION VII ABDOMINAL WALL HERNIAS79. Preoperative Management of the Hernia Patient80. Ventral Hernias81. Hernias of the Abdominal Wall: Atypical Locations82. Inguinal HerniasSECTION VIII ALIMENTARY TRACT83. Benign Esophageal Disorders84. Esophageal Cancer85. The Acute Abdomen86. Stomach87. Gastric Cancer88. Biliary System89. The Liver90. Secondary Tumors of the Liver91. Small Intestine92. Exocrine Pancreas93. Pancreatic Cancer94. The Appendix95. Colon and Rectum96. Cancers of the Colon, Rectum, and Anus97. Benign Anorectal Disorders98. Acute Gastrointestinal Hemorrhage99. Morbid ObesitySECTION IX VASCULAR SURGERY100. Hemostasis and Thrombosis101. Contemporary Management of Carotid Disease102. Aortic Disease103. Peripheral Occlusive Disease104. Extremity Amputations in the Modern Era: Indications, Technique, and Outcomes105. Peripheral Aneurysmal Disease106. Visceral Ischemic Syndromes: Acute and Chronic Mesenteric Ischemia107. Dialysis Access108. Venous Disease109. The LymphaticsSECTION X CARDIOTHORACIC SURGERY110. Lung, Chest Wall, Pleura, and Mediastinum111. Acquired Heart Disease: Coronary Artery Disease112. Acquired Heart Disease: Valvular113. Congenital Heart Disease114. Pulmonary Embolism: Acute and Chronic115. Percutaneous Heart Procedures116. Advances in Extracorporeal Membrane Oxygenation: Techniques, Applications, and ManagementSECTION XI SPECIALTIES IN SURGERY: SUB-SPECIALTY CONSIDERATIONS RELEVANT FOR THE GENERAL SURGEON117. Pediatric Surgery118. Maternal-Fetal Surgery119. Hand Surgery120. Gynecologic Surgery121. Urologic Surgery

"…continues to provide the key information, essential teaching pearls, and updated content needed to make the most informed surgical decisions and achieve optimal outcomes for patients. Concisely written and evidence based throughout, it covers the breadth of material required for certification and practice of general surgery, highlighted by detailed, full-color intraoperative illustrations and high-quality video clips… This is a much-needed new edition of a real classic. The book will be of value to general surgeons at all stages of their training, as well as to practicing surgeons. There are several other comprehensive textbooks, but this text has remained unique for its commitment to quality, inclusion of material not found in other texts, and insistence upon a firm basic science background."Review by Carol Scott-Conner, MD, PhD, MBA, MFA (University of Iowa Hospitals and Clinics), ©Doody's Review Service, 2026. Doody's Score: 99, 5 Stars!

Douglas S. Tyler, MD, MSHCT is a distinguished Professor of Surgery at the University of North Carolina, Chapel Hill, serving as the Associate Chair of Community Operations and Strategy and Director of Hillsborough Services in the Department of Surgery. His past roles include the John Woods Harris Distinguished Chair in Surgery at the University of Texas Medical Branch and Chairman of the Department of Surgery.

• SECTION I SURGICAL TRAINING AND QUALITY CONTROL1. Surgical Education: Past, Present, and Future2. Surgical Simulation and New Ways to Optimize Performance3. Certification of Surgeon Competence4. Preoperative Risk Assessment and Alterations in the COVID-19 Era5. Social Determinants of Health and Their Impact on Surgical Outcomes6. Critical Assessment of Surgical Outcomes and Health Services Research7. Surgical Quality Improvement Programs8. Patient-Reported Outcomes9. Safety in the Surgical Environment10. Advances and Training Considerations in Robotic Surgery11. Advances and Training Considerations in Laparoscopic Surgery12. Advances and Training Considerations in Endoscopy and Endoscopic Surgery13. Telehealth in Surgery14. Health Inequities and Disparities in Surgery15. Global Surgery16. Ethics and Professionalism in Surgery17. Surgeon Health: Ergonomics18. Surgeon Health and Well-BeingSECTION II PERIOPERATIVE MANAGEMENT19. Principles of Preoperative and Operative Surgery20. Anesthesiology Principles, Pain Management, and Sedation21. Optimizing Surgical Outcomes: Prehabilitation and Rehabilitation22. Enhanced Recovery After Surgery (ERAS): Evidence-Based Perioperative Pathways to Optimize Outcomes23. Wound Healing24. The Evolving Role of the Microbiome in Surgical Practice25. Surgical Site Infections26. Surgical Complications: Overview and Grading27. Surgery in the Geriatric Patient28. Surgery in the Pregnant Patient29. Surgical Considerations in the Transgender Patient30. Surgical Palliative Care31. Advanced Analytics and Artificial Intelligence Applications in SurgerySECTION III TRAUMA AND CRITICAL CARE32. The Inflammatory Response33. Shock, Electrolytes, and Fluid34. Metabolism and Nutrition in Surgical Patients35. Primary Soft Tissue Infections36. Management of Acute Trauma37. The Difficult Abdominal Wall38. Management of Vascular Trauma39. Management of Urologic Trauma40. Emergency Care of Musculoskeletal Injuries41. Emergency Care of Neurologic Injuries42. Management of Pediatric Trauma43. Burns44. The Outdoors-Venomous Bites and Stings and Environmental Exposure45. Management of Chronic Wounds46. Surgical Critical Care47. Moving Operating Room Procedures to the Intensive Care Unit48. The Surgeon’s Role in Disaster ManagementSECTION IV TRANSPLANTATION AND IMMUNOLOGY49. Transplantation Immunobiology and Immunosuppression50. Regenerative Medicine and Its Applications to Surgery51. Surgical Considerations in Transplant Patients Undergoing Nontransplant-Related Procedures and Operating in Patients With Portal Hypertension52. Kidney Transplantation53. Liver Transplantation54. Pancreas Transplantation55. Islet Transplantation56. Small Bowel Transplantation57. Heart Transplantation58. Lung Transplantation59. Soft Tissue TransplantationSECTION V SURGICAL ONCOLOGY60. Tumor Biology and Tumor Markers61. Tumor Immunology and Immunotherapy62. Surgical Considerations in Cancer Patients63. Melanoma and Cutaneous Malignancies64. Sarcomas of the Soft Tissues, Retroperitoneum, and Bone65. Gastrointestinal Stromal Tumors66. Benign Diseases of Head and Neck67. Head and Neck Cancer68. Diseases of the Breast69. Plastic Surgical Considerations in Cancer Surgery70. Peritoneal Malignancy and HIPEC71. Surgeon’s Approach to Lymphadenopathy72. The SpleenSECTION VI ENDOCRINE DISORDERS73. The Thyroid74. Parathyroid75. The Adrenal Glands76. Pancreatic Neuroendocrine Tumors77. Neuroendocrine Neoplasms (Carcinoid Tumors)78. The Multiple Endocrine Neoplasia SyndromesSECTION VII ABDOMINAL WALL HERNIAS79. Preoperative Management of the Hernia Patient80. Ventral Hernias81. Hernias of the Abdominal Wall: Atypical Locations82. Inguinal HerniasSECTION VIII ALIMENTARY TRACT83. Benign Esophageal Disorders84. Esophageal Cancer85. The Acute Abdomen86. Stomach87. Gastric Cancer88. Biliary System89. The Liver90. Secondary Tumors of the Liver91. Small Intestine92. Exocrine Pancreas93. Pancreatic Cancer94. The Appendix95. Colon and Rectum96. Cancers of the Colon, Rectum, and Anus97. Benign Anorectal Disorders98. Acute Gastrointestinal Hemorrhage99. Morbid ObesitySECTION IX VASCULAR SURGERY100. Hemostasis and Thrombosis101. Contemporary Management of Carotid Disease102. Aortic Disease103. Peripheral Occlusive Disease104. Extremity Amputations in the Modern Era: Indications, Technique, and Outcomes105. Peripheral Aneurysmal Disease106. Visceral Ischemic Syndromes: Acute and Chronic Mesenteric Ischemia107. Dialysis Access108. Venous Disease109. The LymphaticsSECTION X CARDIOTHORACIC SURGERY110. Lung, Chest Wall, Pleura, and Mediastinum111. Acquired Heart Disease: Coronary Artery Disease112. Acquired Heart Disease: Valvular113. Congenital Heart Disease114. Pulmonary Embolism: Acute and Chronic115. Percutaneous Heart Procedures116. Advances in Extracorporeal Membrane Oxygenation: Techniques, Applications, and ManagementSECTION XI SPECIALTIES IN SURGERY: SUB-SPECIALTY CONSIDERATIONS RELEVANT FOR THE GENERAL SURGEON117. Pediatric Surgery118. Maternal-Fetal Surgery119. Hand Surgery120. Gynecologic Surgery121. Urologic Surgery

"…continues to provide the key information, essential teaching pearls, and updated content needed to make the most informed surgical decisions and achieve optimal outcomes for patients. Concisely written and evidence based throughout, it covers the breadth of material required for certification and practice of general surgery, highlighted by detailed, full-color intraoperative illustrations and high-quality video clips… This is a much-needed new edition of a real classic. The book will be of value to general surgeons at all stages of their training, as well as to practicing surgeons. There are several other comprehensive textbooks, but this text has remained unique for its commitment to quality, inclusion of material not found in other texts, and insistence upon a firm basic science background."Review by Carol Scott-Conner, MD, PhD, MBA, MFA (University of Iowa Hospitals and Clinics), ©Doody's Review Service, 2026. Doody's Score: 99, 5 Stars!

Douglas S. Tyler, MD, MSHCT is a distinguished Professor of Surgery at the University of North Carolina, Chapel Hill, serving as the Associate Chair of Community Operations and Strategy and Director of Hillsborough Services in the Department of Surgery. His past roles include the John Woods Harris Distinguished Chair in Surgery at the University of Texas Medical Branch and Chairman of the Department of Surgery.

• SECTION I SURGICAL TRAINING AND QUALITY CONTROL1. Surgical Education: Past, Present, and Future2. Surgical Simulation and New Ways to Optimize Performance3. Certification of Surgeon Competence4. Preoperative Risk Assessment and Alterations in the COVID-19 Era5. Social Determinants of Health and Their Impact on Surgical Outcomes6. Critical Assessment of Surgical Outcomes and Health Services Research7. Surgical Quality Improvement Programs8. Patient-Reported Outcomes9. Safety in the Surgical Environment10. Advances and Training Considerations in Robotic Surgery11. Advances and Training Considerations in Laparoscopic Surgery12. Advances and Training Considerations in Endoscopy and Endoscopic Surgery13. Telehealth in Surgery14. Health Inequities and Disparities in Surgery15. Global Surgery16. Ethics and Professionalism in Surgery17. Surgeon Health: Ergonomics18. Surgeon Health and Well-BeingSECTION II PERIOPERATIVE MANAGEMENT19. Principles of Preoperative and Operative Surgery20. Anesthesiology Principles, Pain Management, and Sedation21. Optimizing Surgical Outcomes: Prehabilitation and Rehabilitation22. Enhanced Recovery After Surgery (ERAS): Evidence-Based Perioperative Pathways to Optimize Outcomes23. Wound Healing24. The Evolving Role of the Microbiome in Surgical Practice25. Surgical Site Infections26. Surgical Complications: Overview and Grading27. Surgery in the Geriatric Patient28. Surgery in the Pregnant Patient29. Surgical Considerations in the Transgender Patient30. Surgical Palliative Care31. Advanced Analytics and Artificial Intelligence Applications in SurgerySECTION III TRAUMA AND CRITICAL CARE32. The Inflammatory Response33. Shock, Electrolytes, and Fluid34. Metabolism and Nutrition in Surgical Patients35. Primary Soft Tissue Infections36. Management of Acute Trauma37. The Difficult Abdominal Wall38. Management of Vascular Trauma39. Management of Urologic Trauma40. Emergency Care of Musculoskeletal Injuries41. Emergency Care of Neurologic Injuries42. Management of Pediatric Trauma43. Burns44. The Outdoors-Venomous Bites and Stings and Environmental Exposure45. Management of Chronic Wounds46. Surgical Critical Care47. Moving Operating Room Procedures to the Intensive Care Unit48. The Surgeon’s Role in Disaster ManagementSECTION IV TRANSPLANTATION AND IMMUNOLOGY49. Transplantation Immunobiology and Immunosuppression50. Regenerative Medicine and Its Applications to Surgery51. Surgical Considerations in Transplant Patients Undergoing Nontransplant-Related Procedures and Operating in Patients With Portal Hypertension52. Kidney Transplantation53. Liver Transplantation54. Pancreas Transplantation55. Islet Transplantation56. Small Bowel Transplantation57. Heart Transplantation58. Lung Transplantation59. Soft Tissue TransplantationSECTION V SURGICAL ONCOLOGY60. Tumor Biology and Tumor Markers61. Tumor Immunology and Immunotherapy62. Surgical Considerations in Cancer Patients63. Melanoma and Cutaneous Malignancies64. Sarcomas of the Soft Tissues, Retroperitoneum, and Bone65. Gastrointestinal Stromal Tumors66. Benign Diseases of Head and Neck67. Head and Neck Cancer68. Diseases of the Breast69. Plastic Surgical Considerations in Cancer Surgery70. Peritoneal Malignancy and HIPEC71. Surgeon’s Approach to Lymphadenopathy72. The SpleenSECTION VI ENDOCRINE DISORDERS73. The Thyroid74. Parathyroid75. The Adrenal Glands76. Pancreatic Neuroendocrine Tumors77. Neuroendocrine Neoplasms (Carcinoid Tumors)78. The Multiple Endocrine Neoplasia SyndromesSECTION VII ABDOMINAL WALL HERNIAS79. Preoperative Management of the Hernia Patient80. Ventral Hernias81. Hernias of the Abdominal Wall: Atypical Locations82. Inguinal HerniasSECTION VIII ALIMENTARY TRACT83. Benign Esophageal Disorders84. Esophageal Cancer85. The Acute Abdomen86. Stomach87. Gastric Cancer88. Biliary System89. The Liver90. Secondary Tumors of the Liver91. Small Intestine92. Exocrine Pancreas93. Pancreatic Cancer94. The Appendix95. Colon and Rectum96. Cancers of the Colon, Rectum, and Anus97. Benign Anorectal Disorders98. Acute Gastrointestinal Hemorrhage99. Morbid ObesitySECTION IX VASCULAR SURGERY100. Hemostasis and Thrombosis101. Contemporary Management of Carotid Disease102. Aortic Disease103. Peripheral Occlusive Disease104. Extremity Amputations in the Modern Era: Indications, Technique, and Outcomes105. Peripheral Aneurysmal Disease106. Visceral Ischemic Syndromes: Acute and Chronic Mesenteric Ischemia107. Dialysis Access108. Venous Disease109. The LymphaticsSECTION X CARDIOTHORACIC SURGERY110. Lung, Chest Wall, Pleura, and Mediastinum111. Acquired Heart Disease: Coronary Artery Disease112. Acquired Heart Disease: Valvular113. Congenital Heart Disease114. Pulmonary Embolism: Acute and Chronic115. Percutaneous Heart Procedures116. Advances in Extracorporeal Membrane Oxygenation: Techniques, Applications, and ManagementSECTION XI SPECIALTIES IN SURGERY: SUB-SPECIALTY CONSIDERATIONS RELEVANT FOR THE GENERAL SURGEON117. Pediatric Surgery118. Maternal-Fetal Surgery119. Hand Surgery120. Gynecologic Surgery121. Urologic Surgery

"…continues to provide the key information, essential teaching pearls, and updated content needed to make the most informed surgical decisions and achieve optimal outcomes for patients. Concisely written and evidence based throughout, it covers the breadth of material required for certification and practice of general surgery, highlighted by detailed, full-color intraoperative illustrations and high-quality video clips… This is a much-needed new edition of a real classic. The book will be of value to general surgeons at all stages of their training, as well as to practicing surgeons. There are several other comprehensive textbooks, but this text has remained unique for its commitment to quality, inclusion of material not found in other texts, and insistence upon a firm basic science background."Review by Carol Scott-Conner, MD, PhD, MBA, MFA (University of Iowa Hospitals and Clinics), ©Doody's Review Service, 2026. Doody's Score: 99, 5 Stars!