RNA Synthetic Biology

Nyhet

Fundamentals and Applications

Inbunden, Engelska, 2026

1 679 kr

Kommande

This reference book discusses the fundamental principles and applications of RNA synthetic biology. The initial section of the book provides fundamental concepts including RNA synthetic biology, the use computational biology tools for RNA design, the SELEX (Systematic Evolution of Ligands by EXponential enrichment) method, artificial intelligence for design and prediction of RNA circuits, RNA structure prediction and folding algorithms, non-coding RNA, and in vitro selection of functional RNA. This book also highlights the practical applications of RNA synthetic Biology. It offers design, construction and testing of riboswitches, riboregulators, RNA based biosensors, CRISPR for RNA detection, RNA editing, application in nanotechnology, RNA economics, ethics and regulatory issues. This book is intended for researchers and students of molecular biology, genetics, synthetic biology, and RNA biology.Key feature1) Presents fundamental principles and advanced applications of RNA Synthetic Biology2) Reviews the applications of computational tools and artificial intelligence in the design, prediction, and analysis of RNAs and RNA circuits3) Explores the role of RNA modifications on function and the regulatory roles of non-coding RNAs4) Examines CRISPR-based RNA detection and RNA-based therapeutics for genetic diseases, cancer, and infectious diseases.

Produktinformation

Utgivningsdatum2026-03-31
Mått156 x 234 x undefined mm
Vikt453 g
FormatInbunden
SpråkEngelska
Antal sidor304
FörlagTaylor & Francis Ltd
ISBN9781032660806

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Dr. Vijai Singh is currently serving as Professor and Head of the Department of Biosciences, School of Science and Dean (Research & Innovation) at Indrashil University, Rajpur, Mehsana, India. Prior to this, he held the position of Associate Professor in the same department at Indrashil University. He has also served as Assistant Professor in the Department of Biological Sciences and Biotechnology at the Institute of Advanced Research, Gandhinagar, and in the Department of Biotechnology at the Invertis University, Bareilly, India. Earlier of his career, Dr Singh worked as a Postdoctoral Fellow in the Synthetic Biology Group at the Institute of Systems and Synthetic Biology, Paris, France and at the School of Energy & Chemical Engineering at the Ulsan National Institute of Science and Technology, Ulsan, South Korea. He earned his Ph.D. in Biotechnology in 2009 from the ICAR-National Bureau of Fish Genetic Resources, Uttar Pradesh Technical University, Lucknow, India. His doctoral research focused on the development of molecular and immunoassays for the diagnosis of Aeromonas hydrophila. Dr. Singh’s research interests lies in the design and construction of novel biosynthetic pathways for production of medically and industrially important biomolecules. His laboratory is also actively engaged in developing CRISPR-Cas systems for gene knock out, knock in, gene regulation and diagnostic. With over 15 years of research and teaching experience, his areas of expertise include synthetic biology, metabolic engineering, bioinformatics, microbiology, and industrial microbiology. He has an extensive academic record, with over 110 articles, 89 book chapters, 26 books and 3 patents to his credits. Dr. Singh has received number of prestigious awards, including the Bioclues Innovation, Research and Development Award (2023) from the BIOCLUES Society, the Vice Chancellor's Best Research Award (2023) from Indrashil University, and the Agathiyar Chemical Biology Award (2023) from the Society of Chemical and Synthetic Biology. At Indrashil University, he currently serves as chairman of the Board of Study, and is a member of the Academic Council of Indrashil University. He also holds the position of the Member Secretary of the Institutional Biosafety Committee (IBSC) at the university.

Chapter 1: Introduction to RNA based circuits and devices.Chapter 2:Computational Tools for Design and Analysis of RNAs. Chapter 3:Artificial intelligence for design and predict. Chapter 4: RNA circuits RNA structure prediction and folding algorithms. Chapter 5: Non-coding RNAs and their regulatory roles. Chapter 6:Various Approaches to in vitro Selection of Functional RNA: in silico Tests. Chapter 7: Design of riboswitches and its uses. Chapter 8: Design, characterization and applications of riboregulators. Chapter 9: CRISPR-based RNA detection. Chapter 10: CRISPR-based RNA editing and regulation. Chapter 11:RNA Nanotechnology and applications. Chapter 12: RNA economics, ethics and regulatory issue.