RNA Sequence, Structure, and Function: Computational and Bioinformatic Methods

Inbunden, Engelska, 2014

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The existence of genes for RNA molecules not coding for proteins (ncRNAs) has been recognized since the 1950's, but until recently, aside from the critically important ribosomal and transfer RNA genes, most focus has been on protein coding genes.

Produktinformation

Utgivningsdatum2014-03-18
Mått178 x 254 x 34 mm
Vikt1 158 g
FormatInbunden
SpråkEngelska
SerieMethods in Molecular Biology
Antal sidor533
Upplaga2014
FörlagHumana Press Inc.
ISBN9781627037082

Tillhör följande kategorier

Medicinsk genetik inom Medicin
Biologi inom Naturvetenskap och teknik
Biovetenskap inom Naturvetenskap och teknik

Concepts and Introduction to RNA Bioinformatics.- The Principles of RNA Structure Architecture.- The Determination of RNA Folding Nearest Neighbor Parameters.- Energy Directed RNA Structure Prediction.- Introduction to Stochastic Context Free Grammars.- An Introduction to RNA Databases.- Energy-based RNA Consensus Secondary Structure Prediction in Multiple Sequence Alignments.- SCFGs in RNA Secondary Structure Prediction: A Hands-on Approach.- Annotating Functional RNAs in Genomes using Infernal.- Class-specific Prediction of ncRNAs.- Abstract Shape Analysis of RNA.- Introduction to RNA Secondary Structure Comparison.- RNA Structural Alignments, Part I: Sankoff Based Approaches for Structural Alignments.- RNA Structural Alignments, Part II: Non-Sankoff Approaches for Structural Alignments.- De novo Discovery of Structured ncRNA Motifs in Genomic Sequences.,- Phylogeny and Evolution of RNA Structure.- The Art of Editing RNA Structural Alignments.- Automated Modeling of RNA 3D Structure.- Computational Prediction of RNA-RNA Interactions.- Computational Prediction of microRNA Genes.- MicroRNA Target Finding by Comparative Genomics.- Bioinformatics of siRNA Design.- RNA-protein Interactions: An Overview.

From the book reviews: "This book on RNA structure and function is suitable for both graduate and post-graduate students as well as established researchers. ... the book is also a valuable review of the state of the art of hot topics on cutting edge directions of research. In addition, the value of each chapter is enriched by an extensive set of references of recent yet established papers, offering a reliable starting point for literature on each research topic." (Irina Ioana Mohorianu, zbMATH 1307.92008, 2015)