"This edited volume addresses two topical issues to understand the ongoing puzzles of Latin American politics and regionalism: How to explain the ‘regional malaise’ and decline of post-hegemonic regionalism in Latin America? What have been the immediate implications of the Covid-19 crisis? What lessons can be learned, as related to other issue-areas beyond health, in order to repair and revive regional cooperation and coordination, in the post-Covid-19 area? What are the challenges and opportunities?"Arie Kacowicz, The Hebrew University of Jerusalem"A timely and welcome contribution to the literature on regionalism in Latin America. This volume provides a novel and much-needed re-thinking of the challenges of regional cooperation initiatives beyond trade and security, and their effectiveness in resolving transnational problems in the post-pandemic world order."Laura Gomez-Mera, Associate Professor, University of Miami"Deciancio and Quiliconi have successfully embarked on the difficult task of making sense of the South American responses to the pandemic of COVID-19. By bringing together a group of forefront specialists in Latin American regionalism, their book is an indispensable read for those interested in knowing how actors and institutions responded to the pandemic, why collective action fell short, and how they could do better."Stefano Palestini, Assistant Professor of International Relations at the Pontificia Universidad Católica de Chile